Publications by authors named "Moshe Carmel"
Introduction: Anorexia Nervosa (AN) is a psycho-socio-biological disease characterized by severe weight loss as result of dieting and hyperactivity. Effective treatments are scarce, despite its significant prevalence and mortality. AN patients show lower basal insulin levels and increased metabolic clearance, leading to weight loss, cognitive deficits, and hormonal imbalances.
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- The 4th iteration of the Chicago Classification (CC v4.0) introduced stricter criteria for diagnosing Ineffective Esophageal Motility (IEM), leading to fewer patients being classified with this condition compared to the previous version.
- A retrospective study analyzed high-resolution manometry data from 452 patients, revealing that 39% of those initially diagnosed with IEM were reclassified as having normal motility under the new criteria.
- Patients retaining the IEM diagnosis exhibited worse esophageal function and acid exposure, suggesting that the updated criteria provide a more clinically relevant understanding of IEM.