Publications by authors named "Moscato L"
Article Synopsis
- Longitudinal forearm instability, or Essex-Lopresti syndrome, is characterized by a combination of radial head fractures and ruptured connective structures between the radius and ulna, which often goes unnoticed initially.
- Prompt treatment within 4 weeks is important to prevent complications, involving procedures like rigid radial head replacement and surgical repair of surrounding tissues
- If treatment is delayed beyond 4 weeks, more complex interventions are needed, including reconstruction of the interosseous membrane, with less certain outcomes.
Hypothesis: Wide awake local anesthesia with no tourniquet (WALANT) and office-based procedures are used in hand surgery. There are limited literature data on patient satisfaction when comparing methods of anesthesia and location of surgery.
Methods: We conducted a retrospective single-surgeon study with patient reported satisfaction in three groups.
We hypothesized that WALANT would provide similar perioperative analgesic comfort compared to local anesthesia with peripheral nerve blocks (LAPNV). We analyzed whether the patient's active participation during surgery would improve its early functional results. We did a retrospective, single study in an outpatient surgery unit, comparing two types of surgery: trapeziometacarpal arthroplasty (TMCA) under LAPNV and TMCA under WALANT.
View Article and Find Full Text PDFBackground: In recent decades, there has been an increase in male infertility, and in many cases, the etiology remains unclear. Several studies relate male hypo-fertility to xenobiotic exposure, even if no data exist about multiple exposure at the environmental level.
Methods: The study involved 86 males with diagnosis of idiopathic male infertility (IMI), and 46 controls with no alteration in sperm characteristics.
The deep cerebellar nuclei (DCN) have been suggested to play a critical role in sensorimotor learning and some forms of long-term synaptic plasticity observed have been proposed as a possible substrate. However, till now it was not clear whether and how DCN neuron responses manifest long-lasting changes . Here, we have characterized DCN unit responses to tactile stimulation of the facial area in anesthetized mice and evaluated the changes induced by theta-sensory stimulation (TSS), a 4 Hz stimulation pattern that is known to induce plasticity in the cerebellar cortex .
View Article and Find Full Text PDFArticle Synopsis
- Whisker-based object localization relies on the activation and adaptability of the somatosensory and motor cortex, which are influenced by the cerebellum through the thalamus.
- Knock-out mice with impaired cerebellar function (L7-PP2B) struggled significantly more than wild-type mice in learning a whisker localization task, despite showing normal basic motor abilities.
- The study suggests that cerebellar processing, particularly the ability to enhance synaptic connections (potentiation), plays a critical role in the successful learning of complex tasks that require precise timing.
The 2004 Italian legislation on the application of assisted reproductive technology: epilogue.
Eur J Obstet Gynecol Reprod Biol
April 2012
Objective: To evaluate how the unique Italian fertility regulations (≤3 inseminated oocytes/cycle, transfer of all embryos, prohibition of embryo cryopreservation) affected outcomes of ART.
Study Design: Case-control study from the Center of Reproductive Medicine, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy. We compared outcomes of ART patients between five years before (n=1791) and five years after (n=2474) the implementation of the law.
Background: Embryos selection is crucial to maintain high performance in terms of pregnancy rate, reducing the risk of multiple pregnancy during IVF. Pronuclear and nucleolar characteristics have been proposed as an indicator of embryo development and chromosomal complement in humans, providing information about embryo viability.
Methods: To correlate the zygote-score with the maternal age and the outcome of pregnancy, we analyzed the pronuclear and nucleolar morphology, the polar body alignment and the zygote configuration in 459 clinical pregnancies obtained by IVF and ICSI in our public clinic in Reggio Emilia, Italy.
Background: The success in performing organ transplantations and prevention of rejection has resulted not only in a substantial increase in life expectancy, but also improvement in the patients' quality of life. Thus, women who underwent organ transplantation are now reaching puberty and the age of reproduction. This has presented new challenges regarding the teratogenicity and the long-term effect of immunosuppressive medications used by these patients.
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