Expression profiling of antimicrobial peptides and immune-related genes in Nile tilapia following Pseudomonas putida infection and nano-titanium dioxide gel exposure.

Pseudomonas putida is a virulent bacterium that prompts major losses in fish. Recently, there has been a noticeable direction for utilizing nanomaterials in the aquaculture industry for sustaining fish health and performance. Hence, the present study is the first trial to investigate the antibacterial influence of nano titanium dioxide gel (NTG) as a watery addition for combating P.

Efficacy of Lactobacillus acidophilus and yeast cell wall-derived supplements on immunity responses, growth performance, and disease resistance in Cyprinus carpio juveniles.

This study investigated the effects of probiotic Lactobacillus acidophilus (PTCC 1643) (LA) and a commercial yeast cell wall prebiotic (Immunogen) (IM) on immunoantioxidant, growth, and digestive status, and resistance to Aeromonas hydrophila in Cyprinus carpio juveniles. The fish were fed in five treatments including control (T1), LA1.5 (T2): 1.

Clinical validation on role of cancer diagnostic probe in detecting the involved cavity margins missed in permanent pathology of tumor side in breast cancer surgery.

Cancer diagnostic probe (CDP) as a newly entered tool in real-time breast cavity margin evaluation showed great improvement in smart margin shaving intra-operatively. This system increased the rate of involved margin detection to 30% with respect to frozen section. In this study for the first time we showed the independent role of CDP in finding the involved cavity side margins which were not diagnosed by permananet pathology of their tumor side interface.

Effects of Dietary Phytol Supplementation on Growth Performance, Immunological Parameters, Intestinal Bacteria, and Prevention of Oxidative Stress Following Transportation of Nile Tilapia, .

Nile tilapia, , (2.00 ± 0.02 g) were reared in 16 70-L tanks (40 individual/tank) and fed diets (approx.

The Use of Extract in Ameliorating Heat Stress-Induced Oxidative Damage and Improving Growth Efficiency in Carp Juveniles ().

Herbal extracts have been successfully used as feed additives in fish culture with attractive growth-promoting, immunostimulant, antimicrobial, and antioxidant properties for several fish and shellfish species. Therefore, we have designed a feeding trial to assess the impacts of dietary incorporation of extract (PAE) on common carp (). For this purpose, five isonitrogenous (35% protein) and isocaloric (~4,000 kcal/kg) diets have been supplied by supplementing PAE at the varying inclusion levels as 0.

Effects of Dietary Yeast, , and Costmary, , Essential Oil on Growth Performance, Digestive Enzymes, Biochemical Parameters, and Disease Resistance in Nile Tilapia, .

The present study assessed the effects of dietary yeast, , and costmary, , essential oil on growth performance, biochemical parameters, and disease resistance of Nile tilapia, . Four diets containing 1 g/kg yeast (Sc), 0.1 g/kg costmary essential oil (Tb), 1 g/kg yeast + 0.

Dietary Thymol Supplementation Promotes Antioxidant Responses and Thermal Stress Resistance in Rainbow Trout, .

Rainbow trout fingerlings were fed, in triplicate, diets supplemented with 0 (CTL), 50 (50 TM), 100 (100 TM), 200 (200 TM), 400 (400 TM) and 800 (800 TM) mg/kg of thymol, followed by 48 h of thermal stress. Growth performance and humoral immunological parameters showed no significant responses to dietary thymol concentrations. Fish fed 50-400 mg/kg thymol diets had significantly higher survival after heat stress.

Probiotic, fructooligosaccharide and yeast extract mixture improves gut health in rainbow trout, Oncorhynchus mykiss.

The present study investigated the effects of a feed additive (FA) containing a probiotic consortium, fructooligosaccharide and yeast extract on growth performance, humoral immune responses, hepatic antioxidant parameters and intestine digestive enzymes, morphology and transcripts in rainbow trout, Oncorhynchus mykiss. The fish were reared for 8 weeks, feeding on diets containing 0 (CNT), 0.3 (0.

Effects of Dietary Limonene Supplementation on Growth Performance and Immunological Parameters of Common Carp, , Challenged by .

This study examined the impact of dietary limonene treatment on the growth performance, immune response, and disease resistance of common carp, . The fish were fed with either a control diet (CTL; no limonene supplementation) or four experimental diets containing 50 (50 L), 100 (100 L), 200 (200 L), and 400 (400 L) mg/kg limonene over a 70-day period, followed by challenge. The 200 L treatment resulted in a significant decrease in FCR compared to the CTL treatment.

Locoregional therapy containing surgery in metastatic breast cancer: Systematic review and meta-analysis.

Introduction: The role of locoregional therapy (LRT) containing surgery and systematic therapy in metastatic breast cancer patients remains controversial. This study investigated the effect of LRT in patients who were initially diagnosed with metastatic breast cancer (MBC) on overall survival (OS), locoregional progression-free survival (PFS), and distant systemic PFS.

Methods: The related keywords were searched in MEDLINE/PubMed, SCOPUS, and Web of Science databases up to August 15th, 2022.

Effects of Dietary Lactic Acid Supplementation on the Activity of Digestive and Antioxidant Enzymes, Gene Expressions, and Bacterial Communities in the Intestine of Common Carp, .

The present study investigated the effects of dietary lactic acid (LA) supplementation on the growth performance, intestinal digestive/antioxidant enzymes' activities, gene expression, and bacterial communities in common carp, . Four diets were formulated to contain 0 g/kg LA (control), at 2.5 g/kg LA (2.

Chitosan nanogel aqueous treatment improved blood biochemicals, antioxidant capacity, immune response, immune-related gene expression and infection resistance of Nile tilapia.

Candida albicans is a pathogenic yeast recently associated with diverse diseases in aquaculture. The present study investigated the efficacy of chitosan nanogel (CNG) in ameliorating effects of C. albicans on Nile tilapia (Oreochromis niloticus).

Hematological, immuno-antioxidant disruptions, and genes down-regulation induced by Aeromonas veronii challenge in Clarias gariepinus: The ameliorative role of silica nanoparticles.

Aeromonas veronii is a pathogenic bacterium associated with various diseases in aquaculture. However, few studies address the antibacterial activity using nanoparticles (NPs). Hence, the current study is innovative to evaluate the antibacterial efficacy of silica nanoparticles (SiNPs) against A.

Parasites as potential targets for cancer immunotherapy.

Parasites and cancers have some common antigens. Much scientific evidence in the human population, animal models, and in vitro experiments exhibit that parasites have significant anti-cancer effects. The larval stage of the tapeworm Echinococcus granulosus, Toxoplasma gondii, Trypanosoma cruzy, Plasmodium's, and Trichinella spiralis are among the parasites that have been subjects of anti-cancer research in the last decades.

Dietary Lactobacillus helveticus and Gum Arabic improves growth indices, digestive enzyme activities, intestinal microbiota, innate immunological parameters, antioxidant capacity, and disease resistance in common carp.

The present study aimed at determining the effects of Lactobacillus helveticus (LH), Gum Arabic (GA; natural prebiotic), and their combination as synbiotic on growth performance, digestive enzymes activity, gut microbiota, innate immunity status, antioxidant capacity, and disease resistance against Aeromonas hydrophyla in common carp, Cyprinus carpio for 8 weeks. For this, 735 common carp juveniles (Mean ± standard deviation; 22.51 ± 0.

Effect of Stocking Density and Dietary Protein Level in Biofloc System on the Growth, Digestive and Antioxidant Enzyme Activities, Health, and Resistance to Acute Crowding Stress in Juvenile Common Carp ().

This study is aimed at evaluating the effects of stocking densities and dietary protein levels in the biofloc system on the performance of common carp. Fish (12.09 ± 0.

Effects of dietary Plantago ovata seed extract administration on growth performance and immune function of common carp (Cyprinus carpio) fingerling exposed to ammonia toxicity.

Medicinal plants are powerful antioxidants which can improve well-being and suppress oxidative stress caused by environmental toxins in aquatic animals. In this regard, the present research was designed to show the potential effects of psyllium (Plantago ovata) seed extract (PSE) on the growth, and immune responses of common carp Cyprinus carpio exposed to acute ammonia toxicity. To perform the study, fish were fed with diets containing 0 (T0), 0.

Effects of dietary Hyssop, , extract on physiological and antioxidant responses of rainbow trout, , juveniles to thermal stress.

The present study aimed at assessing the effects of dietary Hyssop, , extract on rainbow trout, , responses to thermal stress. The juveniles (69.8 ± 0.

Toxic and bioaccumulative effects of zinc nanoparticle exposure to goldfish, (Linnaeus, 1758).

The widespread use of produced metal oxide nanoparticles (NPs) has increased major concerns about their impact on human as well as aquatic animal health. The present study shows that exposure to different concentrations of zinc oxide (ZnO) NPs led to high accumulations of Zn ions in the metabolic organs of fish (liver and gills), resulting in severe oxidative stress in . The goldfish () was chosen as an aquatic species for the evaluation of the potential toxicity of aqueous ZnO-NPs (Treatments of hemoglobin and neutrophils (0, 0.

Individual and combined effects of the dietary Spirulina platensis and Bacillus licheniformis supplementation on growth performance, antioxidant capacity, innate immunity, relative gene expression and resistance of goldfish, Carassius auratus to Aeromonas hydrophila.

This study evaluated the individual and combined effects of the dietary Spirulina platensis (SP) and probiotic bacterium Bacillus licheniformis (BL) on the growth performance, immune responses, and disease resistance in goldfish (Carassius auratus). A total of 216 fish (3.39 ± 0.

Effect of a diet enriched with sodium propionate on growth performance, antioxidant property, innate-adaptive immune response, and growth-related genes expression in critically endangered beluga sturgeon (Huso huso).

Organic acids are active substances required for improving the productivity and wellbeing of aquatic animals. Herein, the study investigated the effects of sodium propionate on growth performance, antioxidative and immune responses, and growth-related genes expression in beluga sturgeon (Huso huso). For eight weeks, fish fed sodium propionate at 0, 1.

Dietary red macroalgae (Halopithys incurva) improved systemic an mucosal immune and antioxidant parameters and modulated related gene expression in zebrafish (Danio rerio).

In the present study, the effects of dietary Halopithys incurva, a red macroalgae species, (0.25, 0.50, 1%) on whole-body serum and skin mucus immune system, antioxidant system and expression of various genes in zebrafish were investigated.

Effects of dietary thyme essential oil and prebiotic administration on rainbow trout (Oncorhynchus mykiss) welfare and performance.

The aim of this study was to examine the combined effects of thyme essential oil (TEO) and prebiotic (Immunogen ®) on growth performance, hematological parameters, innate immunity, and oxidative status of rainbow trout, Oncorhynchus mykiss. For this purpose, the fish (11.92 ± 0.

Combined and Singular Effects of Ethanolic Extract of Persian Shallot ( Boiss) and Synbiotic BiominIMBO on Growth Performance, Serum- and Mucus-Immune Parameters and Antioxidant Defense in Zebrafish ().

This study was carried out to evaluate combined and singular effects of ethanolic extract of Persian shallot ( Boiss) and synbiotic BiominIMBO on growth performance, innate immune responses, and antioxidant defense in zebrafish (). Fish with initial weight of 151.90 ± 0.

The Gene Regulatory Roles of Herbal Extracts on the Growth, Immune System, and Reproduction of Fish.

The crucial need for safe and healthy aquatic animals obligates researchers in aquaculture to investigate alternative and beneficial additives. Medicinal herbals and their extracts are compromised with diverse effects on the performances of aquatic animals. These compounds can affect growth performance and stimulate the immune system when used in fish diet.