hBN/TiO water-based nanolubricants: a solution for stick-slip mitigation in tribological applications.

In this study, the stick-slip behaviour of synthesised water-based nanolubricants was investigated an Rtec ball-on-disk tribometer. By varying the lubricating conditions, including the concentration of hBN/TiO as nanoadditives, the tribological properties and lubrication mechanisms were analysed, especially the stick-slip phenomenon. Compared with dry and wet conditions, the hBN/TiO nanolubricant presented better efficiency in mitigating stick-slip and achieving friction stability.

IoT based real-time water quality monitoring system in water treatment plants (WTPs).

This study presents the development and implementation of an Internet of Things (IoT)-based real-time water quality monitoring system tailored for water treatment plants (WTPs). The system integrates advanced sensor technologies to continuously monitor key water quality parameters such as pH, dissolved oxygen (DO), total dissolved solids (TDS), and temperature. Data collected by these sensors is transmitted through a robust communication network to a centralized monitoring platform that utilizes cloud-based storage and analytics.

Physicochemical characterization and determination of trace metals in different edible fats and oils in Bangladesh: Nexus to human health.

The study assessed the quality of four different edible fats and oils using standard analytical techniques. The presence of potentially toxic elements was determined using atomic absorption spectrometry. This study reveals that edible oils function admirably in terms of physical traits such as moisture content, boiling point, melting point, density, and specific gravity.

Phonon transport in vacancy induced defective stanene/hBN van der Waals heterostructure.

In this study, Non-Equilibrium Molecular Dynamics (NEMD) simulation is employed to investigate the phonon thermal conductivity (PTC) of Sn/hBN van der Waals heterostructures with different vacancy-induced defects. We deliberately introduce three types of vacancies in Sn/hBN bilayer point vacancies, bivacancies, and edge vacancies at various concentrations ranging from 0.25% to 2%, to examine their effects on PTC across temperatures from 100 K to 600 K.

Simulation Approaches Used for Management and Decision Making in the Beef Production Sector: A Systematic Review.

Simulation models are used in various areas of agriculture to better understand the system and assist in decision making. In the beef production sector, a variety of simulation research focusing on various dimensions of the system is available. However, an overview of the available research is lacking.

Addressing differences in cancer: a framework for synergistic programming in cancer prevention and control.

Background: Cancer remains a leading cause of death worldwide and continues to disproportionately impact certain populations. Several frameworks have been developed that illustrate the multiple determinants of cancer. Expanding upon the work of others, we present an applied framework for cancer prevention and control designed to help clinicians, as well as public health practitioners and researchers, better address differences in cancer outcomes.

Effectively communicating with local policymakers: a randomized trial of policy brief dissemination to address obesity.

Introduction: Evidence-based policies are a powerful tool for impacting health and addressing obesity. Effectively communicating evidence to policymakers is critical to ensure evidence is incorporated into policies. While all public health is local, limited knowledge exists regarding effective approaches for improving local policymakers' uptake of evidence-based policies.

Correlation of CT Scan Response to Necrosis and Volume Changes With Histopathology in Children With Wilms' Tumor.

Background: Wilms' tumor is the most common renal tumor in children.

Objective: To correlate the percentage of necrosis and tumor volume change found in preoperative Contrast Enhance Computed Tomography (CECT) scan of the abdomen with post-operative histopathological findings of Wilms Tumor (WT).

Methods: In this prospective study from January 2020 to December 2022, out of 33 patients, 15 patients with unilateral localized WT (stage I, II, and III) treated according to SIOP UMBRELLA protocol 2016 were included.

Understanding the impact of acne vulgaris and associated psychological distress on self-esteem and quality of life via regression modeling with CADI, DLQI, and WHOQoL.

Acne vulgaris (AV) is a psychosomatic disorder and can negatively affect individuals, especially in terms of psychological well-being, self-esteem, and quality of life (QoL). The current study aimed to investigate the association between AV and psychological health, as well as the influence of acne and psychological distress in predicting patients' self-esteem and QoL. This cross-sectional study included 150 patients clinically diagnosed with AV.

Outcome of different endovascular modalities to treat common iliac artery aneurysms, single center study.

Introduction: Iliac aneurysms occur in 10% of patients with abdominal aortic aneurysms (AAA). There are three different endovascular approaches to their treatment in the context of infrarenal Endovascular Aortic Aneurysm Repair (EVAR): occlusion by coiling the internal iliac, incorporation using an iliac branch device, and delaying repair using a bell bottom limb. We sought to determine outcomes associated with these three strategies in our practice.

Tofacitinib versus methotrexate as the first-line disease-modifying antirheumatic drugs in the treatment of rheumatoid arthritis: An open-label randomized controlled trial.

Objective: To compare tofacitinib and methotrexate (MTX) as first-line disease-modifying antirheumatic drugs (DMARDs) for rheumatoid arthritis (RA).

Methods: This open-label, randomized controlled, parallel-group, 3-month trial randomly assigned 100 RA patients to tofacitinib 10 mg daily (49 patients) or MTX 25 mg subcutaneously weekly (51 patients). The primary end point was low disease activity (LDA) measured with Disease Activity Score-28 with C-reactive protein (DAS28-CRP), and the secondary end point was LDA and remission measured by DAS28-erythrocyte sedimentation rate (ESR), Clinical Disease Activity Index (CDAI), and Simplified Disease Activity Index (SDAI).

Weed Detection Using Deep Learning: A Systematic Literature Review.

Weeds are one of the most harmful agricultural pests that have a significant impact on crops. Weeds are responsible for higher production costs due to crop waste and have a significant impact on the global agricultural economy. The importance of this problem has promoted the research community in exploring the use of technology to support farmers in the early detection of weeds.

Baicalein as Promising Anticancer Agent: A Comprehensive Analysis on Molecular Mechanisms and Therapeutic Perspectives.

Despite significant therapeutic advancements for cancer, an atrocious global burden (for example, health and economic) and radio- and chemo-resistance limit their effectiveness and result in unfavorable health consequences. Natural compounds are generally considered safer than synthetic drugs, and their use in cancer treatment alone, or in combination with conventional therapies, is increasingly becoming accepted. Interesting outcomes from pre-clinical trials using Baicalein in combination with conventional medicines have been reported, and some of them have also undergone clinical trials in later stages.

Target-specificity of different amyrin subunits in impeding HCV influx mechanism inside the human cells considering the quantum tunnel profiles and molecular strings of the CD81 receptor: a combined in silico and in vivo study.

HCV is a hepatotropic RNA virus recognized for its frequent virulence and fatality worldwide. Despite many vaccine development programs underway, researchers are on a quest for natural bioactive compounds due to their multivalent efficiencies against viral infections, considering which the current research aimed to figure out the target-specificity and therapeutic potentiality of α, β, and δ subunits of amyrin, as novel bioactive components against the HCV influx mechanism. Initially, the novelty of amyrin subunits was conducted from 203 pharmacophores, comparing their in-silico pharmacokinetic and pharmacodynamic profiles.

Molecular identification, characterization, and antagonistic activity profiling of LOCK 1002 along with the in-silico analysis of its presumptive bacteriocins.

Objectives: This research aimed to isolate, identify, and characterize a new strain of through different molecular biology approaches so that it could be further studied for therapeutic purposes against selective enteric pathogens.

Materials And Methods: Pure isolates of were prepared from buffalo yogurt samples in REMBA medium. Initially, the morphological, physiological, and biochemical properties were studied accordingly.

Municipal officials' perspectives on policymaking for addressing obesity and health equity.

Background: Obesity evidence-based policies (EBPs) can make a lasting, positive impact on community health; however, policy development and enactment is complex and dependent on multiple forces.

Aims And Objectives: This study investigated key factors affecting municipal officials' policymaking for obesity and related health disparities.

Methods: Semi-structured interviews were conducted with 20 local officials from a selection of municipalities with high obesity or related health disparities across the United States between December 2020 and April 2021.

Oncoinformatic screening of the gene clusters involved in the HER2-positive breast cancer formation along with the in silico pharmacodynamic profiling of selective long-chain omega-3 fatty acids as the metastatic antagonists.

The HER2-positive patients occupy ~ 30% of the total breast cancer patients globally where no prevalent drugs are available to mitigate the frequent metastasis clinically except lapatinib and neratinib. This scarcity reinforced researchers' quest for new medications where natural substances are significantly considered. Valuing the aforementioned issues, this research aimed to study the ERBB2-mediated string networks that work behind the HER2-positive breast cancer formation regarding co-expression, gene regulation, GAMA-receptor-signaling pathway, cellular polarization, and signal inhibition.

A scoping review of frameworks in empirical studies and a review of dissemination frameworks.

Background: The field of dissemination and implementation (D&I) research has grown immensely in recent years. However, the field of dissemination research has not coalesced to the same degree as the field of implementation research. To advance the field of dissemination research, this review aimed to (1) identify the extent to which dissemination frameworks are used in dissemination empirical studies, (2) examine how scholars define dissemination, and (3) identify key constructs from dissemination frameworks.

A Nudge-Inspired AI-Driven Health Platform for Self-Management of Diabetes.

Diabetes mellitus is a serious chronic disease that affects the blood sugar levels in individuals, with current predictions estimating that nearly 578 million people will be affected by diabetes by 2030. Patients with type II diabetes usually follow a self-management regime as directed by a clinician to help regulate their blood glucose levels. Today, various technology solutions exist to support self-management; however, these solutions tend to be independently built, with little to no research or clinical grounding, which has resulted in poor uptake.

Modelling the causes of boiler accidents: implications for economic and social sustainability at the workplace.

This study aims to examine the causes of boiler accidents in the context of the ready-made garment (RMG) industry of Bangladesh as an emerging economy. On the basis of a comprehensive review of the existing literature, previous accident reports, and technical discussion with relevant personnel in the industries and regulating authorities, a total of 14 causes of boiler accidents were identified. This study merged neutrosophic (N) theory with the analytic hierarchy process (AHP) for prioritizing the causes of boiler accidents.

Not So Stable Angina: Single Coronary Artery Disease.

A single coronary artery (SCA) is a rare congenital anomaly that can be incidentally found as a part of ischemic heart disease or angina workup. A modified Lipton classification is used to categorize the disease. The majority of diseases do not need surgical correction, with the exception of a few conditions.

A scoping review of de-implementation frameworks and models.

Background: Reduction or elimination of inappropriate, ineffective, or potentially harmful healthcare services and public health programs can help to ensure limited resources are used effectively. Frameworks and models (FM) are valuable tools in conceptualizing and guiding the study of de-implementation. This scoping review sought to identify and characterize FM that can be used to study de-implementation as a phenomenon and identify gaps in the literature to inform future model development and application for research.

Status of Serum Calcium, Phosphate and Intact Parathyroid Hormone in Predialysis Chronic Kidney Disease Patients of Stage-3 to Stage-5 Compared To KDOQI Guideline.

The chronic kidney disease (CKD) is associated with a variety of bone disorders and disorders of calcium and phosphorus metabolism. Bone disease associated with chronic kidney disease having higher rate of CKD progression and increased risk of death. To see the status of serum calcium, phosphate and intact parathyroid hormone in pre-dialysis CKD (stage- 3 to 5) patients.