Publications by authors named "Morris Zwi"

Background: Attention deficit hyperactivity disorder (ADHD) is one of the most commonly diagnosed and treated psychiatric disorders in childhood. Typically, children and adolescents with ADHD find it difficult to pay attention and they are hyperactive and impulsive. Methylphenidate is the psychostimulant most often prescribed, but the evidence on benefits and harms is uncertain.

View Article and Find Full Text PDF

Much remains unclear about the benefits and harms of methylphenidate for children and adolescents with attention-deficit/hyperactivity disorder (ADHD). Between 2012 and 2018, we conducted two Cochrane systematic reviews on methylphenidate for ADHD. This article explores the main findings in relation to evidence-based practice and our current understanding of ADHD.

View Article and Find Full Text PDF

Background: There is little evidence in the literature on the association between methylphenidate treatment and psychotic symptoms in children and adolescents with attention-deficit/hyperactivity disorder (ADHD).

Objective: We examine the occurrence of psychotic symptoms during methylphenidate treatment of children and adolescents with ADHD. The data arise from our two Cochrane systematic reviews on methylphenidate, reported elsewhere.

View Article and Find Full Text PDF

Background: Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder in childhood. The psychostimulant methylphenidate is the most frequently used medication to treat it. Several studies have investigated the benefits of methylphenidate, showing possible favourable effects on ADHD symptoms, but the true magnitude of the effect is unknown.

View Article and Find Full Text PDF

Objectives: To study in more depth the relationship between type, dose, or duration of methylphenidate offered to children and adolescents with attention deficit hyperactivity disorder and their risks of gastrointestinal adverse events based on our Cochrane systematic review.

Methods And Findings: We use data from our review including 185 randomised clinical trials. Randomised parallel-group trials and cross-over trials reporting gastrointestinal adverse events associated with methylphenidate were included.

View Article and Find Full Text PDF
Article Synopsis
  • The study aimed to evaluate the benefits and risks of methylphenidate for treating ADHD in kids and teens by analyzing data from multiple clinical trials.
  • The results showed methylphenidate had a positive effect on ADHD symptoms and general behavior ratings, particularly from teachers, without increasing serious adverse events, but it did raise the risk of non-serious side effects.
  • However, most of the trials were deemed to have a high risk of bias, and the overall quality of the evidence was classified as very low.
View Article and Find Full Text PDF
Article Synopsis
  • ADHD is a common psychiatric disorder in children characterized by difficulty in paying attention, hyperactivity, and impulsiveness, with methylphenidate being the most frequently prescribed treatment.
  • The systematic review aimed to evaluate the benefits and harms of methylphenidate for children and adolescents diagnosed with ADHD, focusing on RCTs with certain intellectual functioning criteria.
  • Data was comprehensively collected from multiple databases and involved a collaborative effort from 17 review authors, ensuring rigorous analysis of ADHD symptoms, adverse events, and quality of life outcomes.
View Article and Find Full Text PDF

Background: Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder characterised by high levels of inattention, hyperactivity and impulsivity that are present before the age of seven years, seen in a range of situations, inconsistent with the child's developmental level and causing social or academic impairment. Parent training programmes are psychosocial interventions aimed at training parents in techniques to enable them to manage their children's challenging behaviour.

Objectives: To determine whether parent training interventions are effective in reducing ADHD symptoms and associated problems in children aged between five and eigtheen years with a diagnosis of ADHD, compared to controls with no parent training intervention.

View Article and Find Full Text PDF

This is the protocol for a review and there is no abstract. The objectives are as follows: To determine whether parent-training interventions are effective in reducing ADHD symptoms and associated problems (e.g.

View Article and Find Full Text PDF