Publications by authors named "Morris Topaz"
Objective: This study was designed to investigate the therapeutic potential of regulated negative pressure wound therapy (RNPT) in treating infected blast injuries in swine.
Background: Approximately 30% to 80% of blast injuries develop infection, which increases the morbidity and mortality of these casualties. RNPT has been used in US military operations in Iraq; however, no randomized controlled study has been conducted on the use of RNPT to treat infected war injuries.
Background: War injuries, especially blast injuries, have a high risk of infection. However, no animal models of infected war injuries have been built in large animals, which retards both the understanding and the treatment optimization of infected war injuries.
Methods: Soft tissue blast injuries were created by explosion of electric detonators in white domestic pigs.
Background: Removal of subcutaneous skin masses and certain deep skin injuries results in defects, which demand immediate closure. Although primary closure of these defects in 2 layers is an acceptable solution, this technique has a number of drawbacks, such as extended time consumption upon performance, demand for additional suture material and occasional tissue response or foreign body reaction to retained absorbable stitches leading to infection and its sequelae.
Objective: We describe an approach intended to furnish a satisfactory solution to the needs of tissue closure in such cases.
Purpose: To examine the role of the water-soluble antioxidants glutathione and ascorbic acid in the irrigating solution on corneal endothelial cells following exposure to high-intensity ultrasound energy.
Setting: Goldschleger Eye Research Institute, Sheba Medical Center, Tel-Aviv University, Tel Aviv, Israel.
Methods: Thirty-two rabbit eyes were subjected to prolonged exposure to the phacoemulsification device in the anterior chamber.
Antioxidant protection against corneal damage by free radicals during phacoemulsification.
Invest Ophthalmol Vis Sci
May 2003
Purpose: To examine the role of ascorbic acid in reducing corneal endothelial cell loss secondary to high-energy ultrasound energy during phacoemulsification surgery.
Methods: Seventeen rabbit eyes were subjected to prolonged phacoemulsification within the anterior chamber, without manipulation or damage to other ocular structures. In nine eyes, a balanced salt ophthalmic solution was used as the phacoemulsification irrigation solution, and in eight eyes the solution plus 0.