3H-estradiol, 3H-testosterone and 3H-dihydrotestosterone localization in the brain of the lizard Anolis carolinensis: an autoradiographic study.

The presence and the neuroanatomical topography of sex hormone concentrating cells in the brain of the American chameleon, Anolis carolinensis have been demonstrated by these experiments. After 3H-estradiol administration large numbers of hormone concentrating cells were found in the amygdala, septum, medial preoptic area, anterior hypothalamic area, the ventromedial and periventricular nuclei of the hypothalamus, and anterior pituitary. In addition, labelled cells were found in the torus semicircularis, in and around the nucleus isthmus pars parvocellularis.

Localization of lumbar epaxial motoneurons in the rat.

In the rat, lateral longissimus and the lumbar transverso-spinalis muscles are lumbar trunk muscles, and participate in the lordosis reflex (female sexual posturing). Medial longissimus, the remaining major lumbar epaxial muscle, is a muscle of the proximal tail-tailbase. To allow an analysis of the motor control of lordosis, motoneurons for these muscles must be localized.

Descending tracts of the lateral columns of the rat spinal cord: a study using the horseradish peroxidase and silver impregnation techniques.

The location of the cells of origin and the projection areas of descending fibre tracts of the spinal cord lateral columns were examined in rats. Unilateral micro-transections of subpopulations of lateral column fibres, at C2 or T10, with subsequent application of horseradish peroxidase to the severed axons, allowed identification, by retrograde labelling, of those cell groups projecting to the spinal cord through the lateral columns. Additionally, the pattern of fibre and preterminal degeneration below the level of transection was examined using the Fink-Heimer silver impregnation technique.

Receptivity of physicians in a teaching hospital to computerized drug interaction monitoring and reporting system.

Physicians at Stanford University Medical Center were surveyed to evaluate their responses to a computerized drug interaction warning system one year after its installation. While one-fourth of the 862 respondents had personally received at least one warning report, the educational benefits of the system had diffused to many physicians in the hospital. Reports were found to be useful for patient management and 44 per cent of the physicians who had received reports indicated they had changed their behavior in response to the information.

Factors affecting the use of physician services in a rural community.

This paper examines the relative importance of various independent variables for predicting five separate measures of physician utilization in a rural community. The independent variables include socioeconomic, demographic, attitudinal, and health status factors. The results are comparable to those of national studies which find that health status is the primary determinant of utilization.

Autoradiographic localization of estradiol-concentrating cells in the female hamster brain.

Autoradiographic methods were used to study the location of estrogen-concentrating cells in the brain of the female hamster. In the hypothalamus, well-labelled cells were reliably found in the posterior medial preoptic area (MPOA), the anterior hypothalamus (AHA), and the ventromedial (VM), arcuate (ARC) and ventral premammillary nuclei (VPM). In the limbic system, well-labelled cells were found in the ventro-lateral septum, bed nucleus of the stria terminalis, and the medial and cortical nuclei of the amygdala.

Autoradiographic localization of hormone-concentrating cells in the brain of an amphibian, Xenopus laevis. II. Estradiol.

Autoradiographic techniques for light microscopic examination of sex steroid retention were applied to the brains of male and female Xenopus laevis, and anuran amphibian, after 3H-estradiol administration. Estrogen was concentrated by cells in three telencephalic areas (the ventral striatum, the ventral-lateral septum and the amygdala), the anterior preoptic area, the ventral thalamus, the ventral infundibular nucleus, and in the torus semicircularis. The anterior preoptic area and the ventral infundibular nucleus contained the greatest number of labelled cells.

Autoradiographic localization of hormone-concentrating cells in the brain of an amphibian, Xenopus laevis. I. Testosterone.

Autoradiographic methods were used to investigate locations of hormone concentrating cells in the CNS of Xenopus laevis. Both male and female frog brains contained cells. Four major hormone uptake sites were identified: the anterior preoptic area, the ventral infundibular nucleus, a dorsal tegmental area of the medulla and a presumptive motor nucleus of cranial nerves IX-X.