Objective: Rapid trauma evaluation and intervention without time delay are considered integral to time-efficient management of trauma patients, particularly for those with hemodynamic instability. This study examined the impact of immediate availability of mobile angiography with digital subtraction angiography technology in the emergency department (ED) for hemodynamically unstable multiple trauma patients with pelvic injury.
Materials: This retrospective review examined a cohort of all blunt trauma patients with pelvic injury who underwent transcatheter arterial embolization (TAE) using mobile angiography by trauma surgeons in the ED.
Vital-organ transplantation has become acceptable as the treatment of choice for end-stage organ failure. If the patient, facing the end of life, wishes to donate organs after cardiac arrest (CA), donation after cardiac death (DCD) is increasingly important for the realization of the patient's desires after CA. In Japan, kidney transplantation from uncontrolled DCD donors, who are identified in modified Maastricht categories II or V, is one of the critical factors in expanding the donor pool.
View Article and Find Full Text PDFIntroduction: A 79-year man, admitted to our emergency department after accidental falling with syncope, had pelvic fractures and complete atrioventricular (AV) block.
Case Presentation: He received transvenous pacer placement for complete AV block and required hemodynamic stability. His heart rate was successfully controlled.
Background: : To assess the immunologic alteration and long-term prognosis after splenic injury from preservation treatment (PT) (embolization, splenorrhaphy, partial splencetomy) and to compare with splenectomy (SN).
Methods: : The long-term prognosis of patients with blunt splenic injury treated at seven tertiary emergency centers in Japan was retrospectively studied. Patients were followed up by telephone interview and written questionnaire.
Donation after cardiac death (DCD) is increasing in importance as a potential source of vital organs for clinical transplantation. In Japan, the method of kidney procurement from DCD is one of the critical factors in successful deceased renal transplantation. The efforts to shorten the warm ischemic time (WIT), which is defined as the time from cardiac arrest to initiation of cooling in situ, or maintaining adequate renal blood flow during WIT by consistent chest compression are essential.
View Article and Find Full Text PDFBackground: The aim was to determine the effects of a novel free radical scavenger, edaravone, 3-methyl-1-phenyl-2-pyrazoline-5-one (ED), against endothelial barrier dysfunction induced by acute oxidative stress in cultured human umbilical vein endothelial cells (HUVECs).
Methods: To estimate the integrity of the HUVEC monolayer, transendothelial electrical resistance (TEER) was measured for 3 hours. We investigated the permeability change of the monolayer by measuring the concentration of fluorescence in isothiocyanate-labeled dextran (FITC-Dx), and estimated the degree of oxidative stress in terms of hydrogen peroxide (H2O2) in the apical chambers.