Publications by authors named "Moriz Probst"

Background: The Charité Alarm Fatigue Questionnaire (CAFQa) is a 9-item questionnaire that aims to standardize how alarm fatigue in nurses and physicians is measured. We previously hypothesized that it has 2 correlated scales, one on the psychosomatic effects of alarm fatigue and the other on staff's coping strategies in working with alarms.

Objective: We aimed to validate the hypothesized structure of the CAFQa and thus underpin the instrument's construct validity.

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Article Synopsis
  • HDAC inhibitors (HDACi) like VPA and SAHA are studied for their potential protective effects against liver injury during ischemia-reperfusion (I/R) events.
  • Treatment with HDACi caused increased histone hyperacetylation but did not completely prevent liver damage, with VPA actually causing more tissue destruction.
  • The results suggest that while these HDACi can delay injury, they do not provide complete protection, highlighting a complex relationship between HDACi treatment and tissue regeneration through SAPK signaling pathways.
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