Echocardiographic reference z scores of right ventricular dimension and systolic function of children aged 5-12 years.

Background: Reference values for right ventricular dimension and systolic function in Nigerian children are scarce despite their high burden of right ventricular abnormalities. Reference values from other countries may not be suitable for use in Nigerian children because of possible racial variations in cardiac size.

Purpose: To develop reference values for right ventricular dimension and systolic function in healthy Nigerian children aged 5-12 years.

Rhythm abnormalities among hospitalised children in Lagos: a case series.

Arrhythmias refer to disturbances in heart rate or rhythm which leads to heart rates that are abnormally fast, slow or irregular. Rhythm abnormalities may be common among Nigerian children but there are only a few reports. The current write up is a clinical review of eight patients in various age groups including neonates, infants and older children.

Comparative Effectiveness of a Six-Week Treatment Course of Vitamin D and D in Children With Sickle Cell Anemia in Steady State With Hypovitaminosis D: A Randomized Clinical Trial.

Background: Correction of vitamin D deficiency through administration of either vitamin D or D has been shown to reduce chronic bone pains and frequency of acute bone pains, increase bone density as well as improve growth stature in children with sickle cell anemia (SCA). Findings vary on the effectiveness of the two forms of the vitamin. The current study was carried out to compare the effectiveness of a 6-week treatment course of vitamin D and D in the correction of hypovitaminosis D (vitamin D insufficiency and deficiency) as well as evaluate treatment response to derangement of serum calcium and alkaline phosphatase (ALP) in children with SCA in steady state.

Pulmonary Hypertension in Apparently Healthy Children in Southern Nigeria.

Objective: To determine the severity and prevalence of pulmonary hypertension and its relationship with age and body mass index (BMI) in healthy children.

Study Design: Observational study.

Place And Duration Of Study: University of Nigeria Teaching Hospital Ituku-Ozalla Enugu, Lagos State University Teaching Hospital, Niger Delta University Teaching Hospital, Bayelsa and Blessed Children Hospital Enugu from January 2010 to December 2019.

Doppler echocardiographic assessment of pulmonary artery pressure in children with sickle cell anaemia.

Background: Pulmonary artery hypertension (PAH) is a known complication of patients with sickle cell disease (SCD). The prevalence of PAH has been reported to be high in children with SCD in developed countries. The mortality rate of patients with SCD who develop PAH is said to be 40% at 24 to 40 months after diagnosis.

First report of glycogen storage disease type 111a in a Nigerian child.

Glycogen storage disease (GSD) is a rare inborn error of metabolism with an incidence of 1/20,000-40,000 live births. Some of the presenting clinical features can mimic diseases commonly seen in the tropics and subtropics. We report a 14-month-old Nigerian child who presented at our institution with GSD Type 111a to alert physicians on the need to consider and recognise this rare disorder.