Publications by authors named "Mori Liu"
Article Synopsis
- Researchers developed a new drug delivery system using extracellular vesicles (EVs) to transport the enzyme TPP1 to treat Batten disease.
- A single injection of TPP1-loaded EVs showed over 20% delivery efficiency to the brain and demonstrated cumulative therapeutic effects in a mouse model.
- The EV-TPP1 treatment activated the autophagy pathway, reduced harmful lipofuscin aggregates, decreased inflammation, and improved neuron survival, highlighting the potential for enhancing brain health.
