Publications by authors named "Mori Hitoshi"

We experienced a rare case of atrial flutter originating from the giant left appendage (LAA). The local potential of the ablation catheter presented with a rare finding, appearing up to 185 ms earlier than the surface P-wave in the distal LAA. With thoracoscopic LAA clipping, tachycardia was successfully controlled.

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  • * Key factors linked to bleeding included the use of antithrombotic agents, the size of the resection wound, and specimen size.
  • * Direct oral anticoagulants (DOACs) were significantly associated with higher bleeding rates, indicating a need for caution in patients on these medications during postoperative recovery.
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  • The study investigates the effectiveness of catheter ablation in eliminating idiopathic ventricular arrhythmias from different sites in the heart.
  • It analyzes data from 58 patients and finds that overall, 72% had successful ablation, with different success rates linked to two specific sites: ECS and endo-EAS.
  • Successful ECS ablation is associated with shorter distances to the activation site, while successful endo-EAS ablation is linked to earlier electrical signals and shorter intervals between activation sites.
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Unlabelled: Kiso A, Maeda H, Otaka Y, Mori H, Kagaya H. A comparative study of changes in H/M under spinning permanent magnet stimulation, repetitive peripheral magnetic stimulation, and transcutaneous electrical nerve stimulation in healthy individuals. Jpn J Compr Rehabil Sci 2024; 15: 58-62.

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  • CARTONET® is a machine learning tool that automatically classifies ablation sites and predicts potential reconnection sites, but its accuracy is still uncertain.
  • In a study of 396 patients undergoing pulmonary vein isolation (PVI), the sensitivity and positive predictive value (PPV) for site classification were found to be 71.4% and 84.6%, with better results for pulmonary vein lesions compared to non-pulmonary vein lesions.
  • The model showed high accuracy for pulmonary veins but struggled with areas like the CTI and superior vena cava, and it predicted that potential reconnection sites are more likely in areas with lower catheter stability.
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Herein, we present the case of a 76-year-old man diagnosed with an iliopsoas abscess 3 months prior and consequently administered metronidazole. The patient visited our facility complaining of difficulty in speaking and feeling unsteady when walking. Neurological findings showed dysarthria, nystagmus, and bilateral cerebellar ataxia.

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  • Extracellular vesicles (EVs) from Gram-negative bacteria, specifically the cyanobacterium Leptolyngbya boryana, are involved in the transport of chlorophyll biosynthetic intermediates such as monovinyl protochlorophyllide (MV-Pchlide) and play crucial physiological roles.
  • The study differentiated two types of EVs—low-density EVs (L-EVs) and high-density EVs (H-EVs)—found in L. boryana cells under both light and darkness, noting their distinct structures and protein contents.
  • Findings revealed that L-EVs contained various pigments and exhibited higher ratios of chlorophyll intermediates compared to carotenoids, implicating these vesicles in the active
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  • - The study evaluated the effectiveness of inside stent therapy for patients with unresectable malignant hilar biliary obstruction, showing a high clinical success rate of 95.5% in resolving jaundice.
  • - Analysis identified factors influencing stent patency duration; unilateral drainage and chemotherapy were linked to significantly longer stent patency compared to bilateral drainage and no chemotherapy.
  • - The procedure was considered safe, with only a small percentage of patients experiencing early adverse events such as cholangitis and pancreatitis.
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Background: The use of venovenous extracorporeal membrane oxygenation (VV-ECMO), particularly during radiotherapy, for severe malignant central airway obstruction has rarely been reported.

Case Presentation: A 47-year-old female presented to our emergency department with severe respiratory distress. Given her medical history, she was initially diagnosed with asthma.

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  • The study investigates the risk factors for strictures following endoscopic submucosal dissection (ESD) for cervical esophageal cancer and evaluates the effectiveness of steroid injections in preventing these strictures.
  • Among 100 patients analyzed, key risk factors for stricture included larger tumor size, longer resection time, and greater circumferential mucosal defect, particularly in patients who did not receive steroid injections.
  • Results indicated that steroid injections significantly reduced the incidence of stricture in patients with smaller mucosal defects (<3/4 and ≥1/2), but were less effective in those with larger defects (≥3/4).
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  • Atrioventricular nodal reentrant tachycardia (AVNRT) can return even after successful ablation of the slow pathway, prompting a study on recurrence reasons in 46 patients.
  • The study found that while many patients initially had successful RF ablation targeting the rightward inferior extension (RIE), some still experienced recurrent AVNRT, with various types showing up in follow-up cases.
  • Most recurrences were treated successfully again within the RIE area, and notably, the new successful ablation sites were often higher than where the initial procedure targeted.
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  • - This report introduces the "Four-Stage Rocket" technique for transvenous lead extractions (TLEs), designed to overcome challenges like strong adhesions to the heart or vessels that traditional methods struggle with.
  • - The technique was tested in two difficult cases using four specialized devices that worked together via the inferior vena cava, successfully detaching leads that conventional methods couldn't handle.
  • - The "Four-Stage Rocket" approach is a promising alternative for complex TLE scenarios, as it aims to improve safety by minimizing tissue damage while effectively addressing lead adhesion.
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Background: Novel diamond-embedded catheter enables precise temperature-controlled ablation. However, the effects of contact angle on lesion formation of this catheter are poorly understood.

Objective: The purpose of this study was to evaluate lesion formation using the temperature-controlled ablation catheter embedded with diamond at different angles in a porcine experimental model.

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Objective: Postoperative pain is a major issue with subcutaneous implantable cardioverter defibrillators (S-ICD). In 2020, we introduced intravenous patient-controlled analgesia (IV-PCA) in addition to the conventional, request-based analgesia for postoperative pain control in S-ICD. To determine the effect and safety, we quantitatively assessed the effect of IV-PCA after S-ICD surgery over conventional methods.

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Background: The role of the pulmonary veins (PVs) as triggers in atrial fibrillation (AF) is well-known; however, their detailed electrophysiological properties have not been thoroughly examined.

Objective: This study aimed to investigate the electrophysiological properties of the PVs between paroxysmal AF (pAF) and persistent AF (perAF).

Methods: Prior to catheter ablation in patients with pAF ( = 51) and perAF ( = 41), a voltage map of the left atrium and PVs was created under sinus rhythm, and the area of the myocardial sleeves in the PVs and their electrophysiological characteristics, including the pacing threshold and effective refractory period (ERP), were compared between the two groups.

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  • - The study aimed to develop a systematic method for diagnosing atrioventricular nodal reentrant tachycardia (AVNRT) that has a concealed nodoventricular pathway (cNVP).
  • - Researchers analyzed 13 cases of AVNRT involving cNVP, focusing on how the pathway connected to either the slow or fast pathways, and also looked at cases of orthodromic reciprocating tachycardia related to cNVP.
  • - The diagnostic process involves three key steps: identifying accessory pathways via His-refractory PVCs, excluding orthodromic reciprocating tachycardia, and confirming the AVN as the cNVP insertion site, with specific criteria for tachy
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  • - The study looked into how the autonomic nervous system (ANS) and intrinsic mechanisms of sinoatrial node (SAN) cells influence heartbeat patterns and variability, especially as people age.
  • - It involved recording ECG data from young adults (under 21) and older adults (41-78) while examining their heart rate behaviors in normal states and after blocking ANS activity with specific medications.
  • - The results revealed that young adults' heartbeat variability was mainly influenced by intrinsic mechanisms, whereas for older adults, both ANS and intrinsic factors played roles, highlighting the impact of anesthesia on heart regulation in different age groups.
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Background: Lesion formation during catheter ablation is influenced by the power, contact force (CF), time, and catheter stability. However, the influence of the irrigation effects on lesion formation remains unknown.

Methods: An ex vivo experiment using conductive gel was performed.

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Background: Functional dyspepsia (FD) and irritable bowel syndrome (IBS) are caused and exacerbated by consumption of fatty foods. However, no study has evaluated brain activity in response to food images in patients with disorders of gut-brain interaction (DGBI). This study aimed to compare food preference and brain activity when viewing food images between patients with DGBI and healthy controls.

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