Publications by authors named "Mori Hay Levy"

Article Synopsis
  • Asymptomatic SARS-CoV-2 infections can greatly contribute to the spread of COVID-19, prompting a study to identify predictors of these hidden cases in Israel during the fourth vaccination era.
  • The study included 504 individuals aged 18 and older who hadn't been tested for COVID-19 in the last five months, revealing a 12.5% prevalence of occult SARS-CoV-2 cases, with chronic disease being linked to a lower likelihood of these infections.
  • No significant differences were found in demographics or vaccination status between those with and without occult infections, indicating the need for ongoing research and public health strategies to better understand and manage these cases.
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Purpose: Cancer is the second leading cause of death globally. However, by implementing evidence-based prevention strategies, 30%-50% of cancers can be detected early with improved outcomes. At the integrated cancer prevention center (ICPC), we aimed to increase early detection by screening for multiple cancers during one visit.

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The CD24 gene has raised considerable interest in tumor biology as a new prognostic factor and a biomarker for the early detection of cancer. There are currently no studies that assess predictors of CD24 in blood tests among healthy individuals. Our aims were (1) to evaluate predictors of the CD24/CD11b biomarker among healthy subjects and (2) to assess CD24/CD11b levels of participants with and without benign tumors.

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Article Synopsis
  • An estimated 1.24 million cases of blood cancer occur globally each year, but there are currently no standard screening tests for these types of cancer.
  • The study focused on the CD24/CD11b blood test, which was found to have a sensitivity of 78.5% and specificity of 80.2% for detecting hematological malignancies in a cohort of 488 subjects.
  • Results showed that levels of CD24/CD11b were significantly higher in cancer patients compared to healthy individuals, indicating the potential of this test as a screening tool for blood cancers.
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The integration of viral DNA into the host genome is mediated by viral integrase, resulting in the accumulation of double-strand breaks. Integrase-derived peptides (INS and INR) increase the number of integration events, leading to escalated genomic instability that induces apoptosis. CD24 is a surface protein expressed mostly in cancer cells and is very rarely found in normal cells.

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