Publications by authors named "Morgane Miclon"
Article Synopsis
- The study investigates the anthelmintic (anti-parasitic) potential of aqueous extracts from three algae species against gastrointestinal parasitic nematodes in mice.
- The research found that non-polar extracts, particularly from brown algae, showed significant nematicidal activity, suggesting terpenes may be the active compounds.
- The findings underscore the promise of macroalgae as alternative sources for developing new treatments against parasitic infections, especially given the resistance to current drugs.
Levamisole is a broad-spectrum anthelmintic which permanently activates cholinergic receptors from nematodes, inducing a spastic paralysis of the worms. Whereas this molecule is widely used to control parasitic nematodes impacting livestock, its efficacy is compromised by the emergence of drug-resistant parasites. In that respect, there is an urgent need to identify and validate molecular markers associated with resistance.
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