Publications by authors named "Morgane Desseux"
Preeclampsia (PE) is the most threatening pathology of human pregnancy. Placenta from PE patients releases harmful factors that contribute to the exacerbation of the disease. Among these factors is the prokineticin1 (PROK1) and its receptor, PROKR2 that we identified as a mediators of PE.
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- Predicting spontaneous preterm birth is challenging for public health, especially in asymptomatic women.
- This study aimed to assess whether circulating levels of EG-VEGF can effectively predict preterm birth in women at high risk for placenta-related issues, using data from 200 patients.
- Results showed that women who experienced spontaneous preterm birth had significantly higher EG-VEGF levels at various points in pregnancy, suggesting that these levels could serve as a reliable biomarker for assessing this risk.
Article Synopsis
- - The cellular prion protein (PrP) is a glycoprotein found on cell surfaces, primarily in the brain and peripheral tissues, linked to various functions including signaling, copper homeostasis, and cell adhesion.
- - PrP is implicated in neurodegenerative diseases and has been found to be expressed in multiple types of cancers, where it aids in tumor growth, cellular invasion, and resistance to chemotherapy.
- - The review highlights the varied expression of PrP in different cancers and suggests its potential as a therapeutic target for cancer treatment.