Increases in erythrocyte DHA are not associated with increases in LDL-cholesterol: Cooper center longitudinal study.

Background: The effects of fish oil products containing docosahexaenoic acid (DHA) on LDL-C levels are controversial.

Objective: To determine if changes in erythrocyte DHA are associated with changes in LDL-C levels.

Methods: In this prospective observational study, erythrocyte DHA levels and LDL-C levels were measured in 9253 individuals who presented for at least two examinations at a medical clinic.