Spontaneous Disseminated Histiocytic Sarcoma in a Bengal Tiger (Panthera tigris tigris).

A 16-year-old, female, captive Bengal tiger (Panthera tigris tigris) had a history of a recurrent subcutaneous mass. After two attempts at surgical removal, euthanasia was elected during the third surgical attempt due to the degree of neoplastic infiltration. At necropsy, a large subcutaneous mass infiltrated the dermis, subcutis and abdominal wall with metastasis to the lungs, spleen and adrenal glands.

Circulating melanin-containing cells and neutrophils with phagocytized melanin granules in a horse with disseminated melanoma.

An 18-year-old, grey, Thoroughbred Cross gelding was referred to the Cummings School of Veterinary Medicine at Tufts University following a 3-week history of low-grade fever of unknown origin, distal limb swelling, and weight loss. Clinical examination identified a few black, round, smooth nodules along the ventral aspect of the proximal tail. Transabdominal ultrasound showed a markedly enlarged heterogenous spleen, hyperechoic liver nodules, and evidence of peritonitis with fibrin deposition.

Unusual invasion of primary pulmonary adenocarcinoma in a cat.

Case Summary: An 11-year-old female spayed domestic shorthair cat was referred to the Foster Hospital for Small Animals, USA for suspected dysautonomia based on weight loss, vomiting and referral radiographs that showed severe dilation of the esophagus, stomach and entire gastrointestinal tract. After recheck radiographs revealed a decrease in gas compared with the referral images, persistently reduced gastrointestinal motility was deemed less likely; however, cardiomegaly and a soft tissue opacity overlying the esophagus were noted. Echocardiogram identified a pulmonary mass either impinging on or invading the local organs.

Synthesis and crystal structure of a disubstituted nickel(II) bis-[(di-methyl-amino-phenyl-imino)-eth-yl]pyridine chloride complex.

The solvated title compound, bis-[2,6-bis-(1-{[4-(di-methyl-amino)-phen-yl]imino-κ}eth-yl)pyridine-κ]nickel(II) dichloride-di-chloro-methane-water (1/2/2), [Ni(CHN)]Cl·2CHCl·2HO, represents a nickel(II) bis-(pyridine di-imine) complex with electron-donating di-methyl-amino-phenyl substituents. The complex crystallizes as a water/di-chloro-methane solvate with ' = 2, thus the asymmetric unit consists of two Ni complex cations, four chloride anions, four adventitious water and four di-chloro-methane solvent mol-ecules. Around each octa-hedrally coordinated Ni cation, one pendant phenyl group on each of the two ligands has an intra-molecular π-π inter-action with the pyridine ring of the other chelating ligand.