Treating infants with neonatal abstinence syndrome: an examination of three protocols.

Objective: Describe the characteristics of infants with NAS and determine if treatment outcomes varied between three protocols.

Study Design: Based on medical record data, infant treatment for NAS-related withdrawal reflected one of three protocols: (1) No rescue dose (n = 836, 52.7%): Prescriber ordered initiation and escalation doses and determined when infants were eligible for weaning, (2) Rescue dose (n = 233, 14.