Publications by authors named "Morgan Heckman"
Article Synopsis
- Titanium dioxide nanoparticles (TiO NPs) are widely used in food coloring, cosmetics, and industrial materials, with over 1 million metric tons produced globally.
- The research focuses on comparing three types of TiO NPs (P25, E171, R101) to understand their effects on inflammation, particularly observing the pro-inflammatory response of P25 in both cellular and animal studies.
- Findings indicate that P25 TiO NPs provoke more inflammation due to their smaller particle size, resulting in a higher number of particles at mass-matched concentrations, which is critical in understanding their inflammatory potential.
The dorsal striatum (DS) mediates the selection of actions for reward acquisition necessary for survival. Striatal pathology contributes to several neuropsychiatric conditions, including aberrant selection of actions for specific rewards in addiction. A major source of glutamate driving striatal activity is the rostral intralaminar nuclei (rILN) of the thalamus.
View Article and Find Full Text PDFCompulsive alcohol consumption is regulated by dorsal striatum fast-spiking interneurons.
Neuropsychopharmacology
January 2021
Compulsive alcohol consumption is a core, treatment-resistant feature of alcohol use disorder. The dorsomedial and dorsolateral striatum support goal-directed and habitual action strategies, respectively. How ethanol targets dorsolateral striatum to drive compulsive consumption is poorly understood.
View Article and Find Full Text PDF