Publications by authors named "Morgan A McCord"
Objective: To retrospectively describe clinical characteristics of canine gastrointestinal foreign bodies (GIFB) that were successfully and unsuccessfully managed conservatively.
Animals: 68 client-owned dogs presented to the Texas A&M Small Animal Teaching Hospital between January 1, 2018, and October 1, 2023, for GIFB where medical management was attempted.
Clinical Presentation: Medical records were reviewed for signalment, history, physical examination, bloodwork, diagnostic imaging, foreign body type, location, treatments, and outcome.
Article Synopsis
- MutY glycosylase helps fix DNA mistakes by removing adenines that are incorrectly paired with the oxidatively damaged guanine (OG), preventing potential mutations.
- The study shows that specific parts of the MutY protein and the structure of OG are essential for the protein to recognize and repair these DNA errors effectively.
- Findings suggest that problems with this detection process could be linked to early-onset colorectal cancer, paving the way for potential therapies targeting the MUTYH gene.