Development of sleep states in normal premature and full-term newborns.

1) to answer the question "Do sleep states exist in normal premature infants;" 2) to analyze the development of sleep cycle and sleep state characteristics in premature and full-term newborns. Polygraph recordings were done on 38 normal, appropriate for gestational age newborns, born at 30 to 41 weeks (w) of gestation. All infants fell asleep in active sleep (AS).

Influence of breathing pattern on functional residual capacity in sleeping newborn infants.

The present study was designed to assess the influence of breathing pattern on the variations of functional residual capacity during sleep in newborn infants. Functional residual capacity was measured by the He-dilution method. Neurophysiologic criteria were used to identify sleep states.

[Coma in full-term newborn infants following acute fetal distress: electro-clinical evolution].

Twenty full term infants who had birth asphyxia were studied. These infants were in a comatose state for 4 to 15 days and at least 3 EEG recordings were performed during this period. Six infants recovered without sequelae and in 2 cases there were minor abnormalities.

Seizures and electrical discharges in premature infants.

Electro-clinical seizures or electrical discharges are described in fifty premature infants divided in two groups: group A (GA twenty-six to thirty-two weeks) = thirty cases - group B (GA thirty-three to thirty-six wks) = twenty cases. In both groups, electrical discharges were shorter than electro-clinical seizures; during seizures ocular manifestations were frequent; bradycardia occurred only in group A. Discharges were associated with other abnormalities (absence of normal EEG pattern, presence of rolandic positive spikes) more frequently in group B than in group A; they occurred without clinical manifestations or coma in nine cases.

Expiratory patterns during sleep in normal full-term and premature neonates.

Airflow (V), tidal volume (TV), and EEG polygraphic recordings were performed in 30 normal full-term newborns (FTN) and in 10 premature newborns (PN). Besides the classical expiratory flow (CEF), a retarded expiratory flow (REF) was observed: a phase of slow flow ending with a sharp increase. REF was mostly encountered in quiet sleep (QS) in FTN.

[Seizures in premature neonates and in full-term neonates (author's transl)].

Normal EEG rhythms depend on conceptional age (CA), i.e., gestational age plus legal age.

Respiratory variability according to sleep states during mechanical ventilation: a polygraphic study in a baby with bilateral diaphragmatic paralysis.

Polygraphic recordings were performed at 1 and 2 months of age in mechanically ventilated baby (25-27 insufflations per min) with bilateral diaphragmatic paralysis. The EEG and the sleep organisation were normal for the given age. The breathing patterns were state dependent.

[Assisted ventilation of newborn infants during sleep. Study of factors modifying adaptation to ventilation].

During sleep, of ventilated newborns and young infants, spontaneous respiratory movements may occur, unrelated to the ventilation impulsions. The respiratory pattern is then classified as "active". On the contrary, the respiratory pattern is classified as "passive", when all respiratory movements are related to the ventilation insufflation.

Sleep and heart rate variations in premature and full term babies.

Heart rate was studied in 47 newborns babies during 67 polygraphic recordings by histograms and sequential curves of the length of 600 consecutive R-R-intervals selected during sleep stages lasting at least 5 minutes. In normal babies: (14 babies born at Gestational Age, G.A.