Publications by authors named "Moreira D"

Violence in intimate relationships (IPV) is understood as one of the most common forms of violence, being maintained by cultural habits and customs, and legitimized from generation to generation. This study aims at a comprehensive review of the literature on IPV, the relationship between the stages of change, maintenance factors, and the decision to keep or leave the violent partner. A comprehensive literature search was conducted to identify journal articles focused on IPV, following online databases as well as a manual review from relevant peer-reviewed journals.

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Bees are essential pollinators that contribute to maintaining biodiversity and increasing agricultural production. However, by foraging on agricultural crops, bees may become contaminated with compounds used for pest control. In this study, we exposed bee (Apis mellifera L.

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Objective: To evaluate the perspectives of tuberculosis experts from different countries regarding national screening procedures.

Methods: This was a qualitative descriptive study. Data were collected by using electronic, anonymized surveys with experts in tuberculosis in seven different countries within two World Health Organization regions (Europe and Africa).

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Background: Non-malignant tumors of the CNS contribute substantially to the morbidity and mortality from CNS tumors. It is critical to understand the epidemiology of non-malignant CNS tumors separately from CNS malignancies to inform resource allocation and policy since treatment and prognosis can differ. High quality international data on non-malignant CNS tumor burden are needed to accomplish this goal.

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Amphibian skin is a rich source of molecules with biotechnological potential, including the tryptophyllin family of peptides. Here, we report the identification and characterization of two tryptophyllin peptides, FPPEWISR and FPWLLS-NH, from the skin of the Central Dwarf Frog, Physalaemus centralis. These peptides were identified through cDNA cloning and sequence comparison.

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: Animal-Assisted Therapy (AAT) is a clinical approach aimed at building valuable human-animal relationships with both preventive and therapeutic goals. It is provided by a healthcare professional and involves animals (meeting certain criteria) as an integral part of the treatment process. This type of therapy has been shown to have multiple benefits in several areas, such as reducing anxiety in a variety of different groups of people.

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This study investigated the effects of a novel bombesin-related peptide (BR-b), derived from the skin of the Chaco tree frog (Boana raniceps), on glucose homeostasis in non-obese and hypothalamic-obese male rats. Hypothalamic obesity was induced in neonatal rats through high-dose administration of monosodium glutamate (MSG; 4 g/kg), while control animals (CTL) received an equimolar saline solution. At 70 days of age, both MSG and CTL groups underwent an oral glucose tolerance test (OGTT; 2 g/kg) with or without prior intraperitoneal administration of BR-b at doses of 0.

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There is currently a global shortage of healthcare professionals equipped to handle the rising burden of childhood cancer. St. Jude Global is an initiative to improve survival rates of children with cancer worldwide while improving access to quality care.

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Objective: This study aimed to verify the association of anthropometric and motor variables with the competitive indicators of female athletes in the ABADÁ-Capoeira (Associação Brasileira de Apoio e Desenvolvimento da Arte Capoeira) World Games.

Methods: Forty-two capoeira athletes from 15 countries (capoeira experience = 15.1 [7.

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Eukaryotes evolved from prokaryotic predecessors in the early Proterozoic and radiated from their already complex last common ancestor, diversifying into several supergroups with unresolved deep evolutionary connections. They evolved extremely diverse lifestyles, playing crucial roles in the carbon cycle. Heterotrophic flagellates are arguably the most diverse eukaryotes and often occupy basal positions in phylogenetic trees.

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Beliefs are information-processing structures formed along an individual's developmental pathway. Beliefs can legitimize involvement in inappropriate or violent behaviors, particularly when they crystallize into cognitive schemas. While beliefs aid individuals in interpreting the surrounding world, overly rigid and inflexible beliefs can constrain the individual's ability to process available information.

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Understanding the origin of eukaryotic cells is one of the most difficult problems in all of biology. A key challenge relevant to the question of eukaryogenesis is reconstructing the gene repertoire of the last eukaryotic common ancestor (LECA). As data sets grow, sketching an accurate genomics-informed picture of early eukaryotic cellular complexity requires provision of analytical resources and a commitment to data sharing.

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Background: Ascorbate peroxidase (APX) has emerged as a promising target for chemotherapy because of its absence in humans and crucial role in the antioxidant defence of trypanosomatids. APXs, which are class I haeme-containing enzymes, reduces hydrogen peroxide using ascorbate to produce water and monodehydroascorbate, thereby preventing cell damage caused by HO.

Methods: We aimed to create an APX-knockout L.

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Article Synopsis
  • - A 22-year-old male experiences symptoms including chin numbness, eye movement issues (ophthalmoplegia), headaches, and left leg numbness, alongside fever, chills, and night sweats.
  • - Imaging shows unusual enhancements in the cauda equina (nerve roots at the lower spine) and an infiltrative issue at the skull base, with additional findings of bone marrow involvement and swollen lymph nodes.
  • - The discussion includes identifying the location of these symptoms, possible diagnoses to consider, necessary tests to conduct, and important lab results and treatment options related to the unique final diagnosis.
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Background: To enhance the quality of care available for children with central nervous system (CNS) tumors across the world, a systematic evaluation of capacity is needed to identify gaps and prioritize interventions. To that end, we created the pediatric neuro-oncology (PNO) resource assessment aid (PANORAMA) tool.

Methods: The development of PANORAMA encompassed 3 phases: operationalization, consensus building, and piloting.

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Article Synopsis
  • Integrin alpha V is crucial for cell adhesion and signaling during development, and mutations in its gene (ITGAV) can lead to serious health issues.
  • In three families, biallelic variants were found that caused either dysfunctional protein production or the integrin being misplaced, resulting in severe developmental problems like eye and brain abnormalities, inflammatory bowel disease, and immune issues.
  • Studies in patient cells and zebrafish models confirmed these mutations resulted in impaired immune signaling and developmental defects, linking the ITGAV variants to a newly identified human disease.
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This research aimed to assess the potential of emerging contaminants as environmental quality indicators for short-term monitoring programs, in contrast with traditional contaminants. Thirteen sediment samples from from Piratininga, a coastal lagoon subjected to anthropogenic impact, were analyzed for the following compounds: napropamide, diclofenac, naproxen, triclosan, ibuprofen, 17β-estradiol, bisphenol A, nadolol, ethofibrate and carbamazepine. The developed method, which included solid phase extraction, derivatization, and analysis by gas chromatography-mass spectrometry, demonstrated robustness and suitability with quantification limits between 0.

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The increasing prevalence of fake publications created by paper mills poses a significant challenge to maintaining scientific integrity. While integrity analysts typically rely on textual and visual clues to identify fake articles, determining which papers merit further investigation can be akin to searching for a needle in a haystack, as these fake publications have non-related authors and are published on non-related venues. To address this challenge, we developed a new methodology for provenance analysis, which automatically tracks and groups suspicious figures and documents.

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Background: Delirium affects 50-85% of patients on mechanical ventilation and is associated with increased mortality, prolonged hospitalization, and a three-fold higher risk of dementia. Microglia, the resident immune cells of the brain, exhibit both neuroprotective and neurotoxic functions; however, their effects in mechanical ventilation-induced acute lung injury (VILI) are unknown. We hypothesize that in a model of short-term VILI, microglia play a neuroprotective role to ameliorate delirium-like phenotypes.

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Objectives: This systematic review was conducted to evaluate the applicability of the envelope (E) protein in the diagnosis of arboviruses.

Methods: This review was performed in accordance with the PRISMA statement. Five databases were explored (PubMed, Web of Science, Scopus, EMBASE, and IEDB).

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Introduction: Type I Basilar invagination is associated with the assimilation of the anterior arch of the atlas. Observation suggests that the assimilation of the atlas does not allow the development of the normal space between the skull and C1 and displaces the high cervical spine towards the neural structures, posteriorly positioned. Purpose: The objective of this work is to evaluate craniospinal alignment in patients with type I Basilar invagination and AOA in comparison with normal subjects (Type I).

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Introduction: Contradictory claims about the efficacy of several medicinal plants to promote glycemic control in patients with type 2 diabetes mellitus (T2DM) have been explained by divergences in the administration form and by extrapolation of data obtained from healthy individuals. It is not known whether the antidiabetic effects of traditional herbal medicines are influenced by gelatin capsules. This randomized crossover trial aimed to evaluate the acute effect of a single dose of raw cinnamon consumed orally either dissolved in water as a beverage or as ordinary hard gelatin capsules on postprandial hyperglycemia (>140 mg/dL; >7.

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Researchers in the Global South (GS, developing countries) make valuable contributions to the field of comparative physiology, but face economic and scientific disparities and several unique challenges compared with colleagues in the Global North (developed countries). This Perspective highlights some of the challenges, knowledge gaps and disparities in opportunity faced by GS researchers, especially those at early-career stages. We propose collaborative solutions to help address these issues, and advocate for promoting investment and cultural and societal change for a more inclusive research community.

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