The human papilloma virus (HPV) vaccine is the world's first proven and effective vaccine to prevent cancers in males and females when administered pre-exposure. Like most of the US, barely half of Vermont teens are up-to-date with the vaccination, with comparable deficits in New Hampshire and Maine. The rates for HPV vaccine initiation and completion are as low as 33% in rural New England.
View Article and Find Full Text PDFBackground: There is limited evidence on the safety of return to sexual activity after hip arthroscopy.
Aim: To determine the positional safety of sexual activity after hip arthroscopy relative to hip instability and/or impingement risk.
Study Design: This study is an observational study.
Background: Sexual difficulties and dysfunction are common in patients with femoroacetabular impingement syndrome (FAIS) secondary to hip pain and stiffness.
Purpose: To determine the risk of impingement in patients with FAIS during common sexual positions using 3-dimensional computer-simulated collision detection before and after cam correction.
Study Design: Descriptive laboratory study.
Background: Several studies have analyzed the most cited articles in shoulder, elbow, pediatrics, and foot and ankle surgery. However, no study has analyzed the quality of the most cited articles in elbow medial ulnar collateral ligament (UCL) surgery.
Purpose: To (1) identify the top 50 most cited articles related to UCL surgery, (2) determine whether there was a correlation between the top cited articles and level of evidence, and (3) determine whether there was a correlation between study methodological quality and the top cited articles.
Case: Three years after a total knee arthroplasty, the patient presented with persistent pain and an enlarging intra-articular periprosthetic mass. Attempts at nonoperative treatment and arthroscopic debridement were unsuccessful. A biopsy revealed a large, intermediate-grade chondrosarcoma involving the joint space.
View Article and Find Full Text PDFWe investigated the effect of commonly used medications on the accumulation of ascorbic acid in human intestinal Caco-2 cells. Although ascorbic acid is negatively charged at physiological pH, anionic compounds including drugs and metabolites had little effect on its accumulation. On the other hand, hydrophobic 1,4-dihydropyridine compounds (nifedipine and nicardipine), but not other structurally unrelated calcium channel blockers, were found to be potent inhibitors.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
October 1999
Two high copy suppressors of temperature-sensitive TATA-binding protein (TBP) mutants were isolated. One suppressor was TIF51A, which encodes eukaryotic translation initiation factor 5A. The other high copy suppressor, YGL241W, also known as KAP114, is one of 14 importin/karyopherin proteins in yeast.
View Article and Find Full Text PDFDietary flavonoids were found to be antiproliferative for human colon cancer cells, Caco-2 and HT-29, and rat nontransformed intestinal crypt cells, IEC-6. The antiproliferative potency was found to be structure-dependent. We report here a correlation between the antiproliferative potency of these flavonoids and their ability to inhibit cellular accumulation of ascorbic acid (vitamin C).
View Article and Find Full Text PDFInvolvement of the juxtarenal spaces and kidneys in pancreatitis has been well known. Although delineation of the regions of accumulation of exudate has been elegantly confirmed with the advent and advance of refined computerized tomography (CT) there has been relatively little description in the earlier literature of these phenomena. This essay serves to illustrate the wide range of findings that have been encountered and recorded more recently.
View Article and Find Full Text PDFPurpose: To define computed tomographic (CT) features of cystic adrenal lesions that differentiate them from similar-appearing adenoma.
Materials And Methods: CT scans of 13 cystic adrenal lesions (four endothelial cysts, three benign pseudocysts, one nonspecific benign cyst, one carcinoma, one pheochromocytoma, and three stable lesions with no histologic diagnosis) were analyzed retrospectively. Reports in the literature of 26 benign adrenal cysts were also reviewed.
Radiographics
November 1995
Occasionally, artifacts may simulate pathologic conditions on magnetic resonance (MR) images. Motion artifacts especially affect images of the chest and abdomen. There are a number of techniques for reducing motion artifacts, including respiratory and cardiac gating, k-space phase reordering, gradient moment nulling, even echo rephasing, and physical restraints.
View Article and Find Full Text PDFWe describe a patient with tuberous sclerosis and an insulinoma. The neurologic abnormalities typically present in patients with tuberous sclerosis may, in rare cases, be manifestations of hypoglycemia. We discussed a possible association between tuberous sclerosis and multiple endocrine neoplasia type I.
View Article and Find Full Text PDFMagn Reson Imaging
April 1995
The objective of this study was to determine correlation between structural anatomy and surface coil spin-echo MR imaging of the rat kidney and the effect of hydration state on MR signal intensities of the cortex and medulla. Twelve rats were studied in a pilot study with a 3-inch surface coil in a 1.5 T magnet under five different states of hydration.
View Article and Find Full Text PDFCardiovasc Intervent Radiol
August 1993
Two patients with pseudocoarctation complicated by dissection are presented. They are the first cases in which pseudocoarctation with dissection have been imaged by magnetic resonance (MR). MR imaging is an excellent noninvasive modality in the evaluation of dissection in pseudocoarctation of the aorta.
View Article and Find Full Text PDFIn his or her practice, the nephrologist usually has a substantial number of patients on dialysis for chronic renal failure. The longer a patient remains on either peritoneal dialysis or hemodialysis, the more at risk he or she is of developing acquired cystic disease of the kidney and renal cell carcinoma. Due to recent developments such as lower osmolar intravenous contrast media, sonography, and magnetic resonance imaging, the radiologist has the ability to assess the kidney in chronic renal failure with a growing number of less-invasive modalities.
View Article and Find Full Text PDFA low-signal band parallel and anterior to the posterior cruciate ligament has been noted on sagittal MR images of the knee in some patients with other evidence for medial meniscal tears. It was hypothesized that this low-signal band represented the mesially displaced fragment of a bucket-handle tear. To verify this, we retrospectively reviewed MR and arthroscopic findings in 54 consecutive patients.
View Article and Find Full Text PDFThe diagnostic value of computed tomography (CT) and barium enema (BE) studies was evaluated prospectively in hospitalized patients with the presumptive diagnosis of acute sigmoid diverticulitis based on the presence of left-lower-quadrant pain and tenderness, fever, and leukocytosis. Of 56 patients, 11 had sigmoid diverticulitis confirmed at surgery and 16 by clinical response to medical therapy. CT, performed in all diverticulitis patients, had positive results in 93% (25 of 27).
View Article and Find Full Text PDFWe report a case of a tuberculous pancreatic abscess in a 47-year-old human immunodeficiency virus positive intravenous drug abuser. She had a prolonged febrile course and persistent abdominal pain. On CT and sonography the lesion lacked the usual ancillary features of an abscess such as diffuse pancreatic enlargement and a peripancreatic fluid collection, and more closely resembled a necrotic neoplasm.
View Article and Find Full Text PDFDis Colon Rectum
January 1990
A total of 31 patients with diverticulitis were analyzed who had both computed tomography and contrast enema. There was almost equal sensitivity to abnormality of approximately 90 percent. Contrast enema produced a specific diagnosis of diverticulitis in 61 percent, using stringent positive criteria, and an additional 29 percent with suggestive findings.
View Article and Find Full Text PDFHamartoma of the spleen is a very rare, benign tumor. A case report of an isodense mass on computed tomography, both before and after intravenous contrast administration is illustrated. The mass was well demonstrated on sonography and nuclear medicine scans.
View Article and Find Full Text PDFComputed tomography (CT) is currently the imaging modality of choice for assessing the morphology of the adrenal glands in adult patients. Much useful information can be gained using CT in disease processes which primarily involve one or both of the adrenal glands, such as adenomas, as well as in entities which secondarily affect the adrenals, such as pituitary or metastatic disease. The size and configuration of the glands can be readily determined, and masses may be detected.
View Article and Find Full Text PDFThe value of CT and sonography in the diagnosis and follow-up of abscesses of the prostate was studied in six patients with this disease. Five had CT alone, one had CT and sonography, and one had sonography only. CT findings included an enlarged gland with nonenhancing fluid-density collections that sometimes were multiseptated or had enhancing rims.
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