Publications by authors named "Mor Fall"
Article Synopsis
- The polypill strategy aims to improve cardiovascular prevention through cost-effectiveness and simplicity, though recent trials indicate that aspirin may not provide significant benefits in high-risk groups.
- A simulation study assessed various combinations of medications, including aspirin, and found that most subgroups, especially women, showed little to no benefit from aspirin compared to its bleeding risks.
- The optimal polypill strategy, which excludes aspirin, could effectively reduce the incidence of strokes and heart attacks among individuals aged 35 to 65, preventing serious cardiovascular events in a significant portion of treated patients.
Aim Of The Study: To explore whether preventive cardiovascular drugs (antihypertensive, antiplatelet, lipid lowering and hypoglycemic agents) interact together in cardiovascular prevention.
Methods: We searched PubMed®, Web of science™, Embase and Cochrane library for powerful randomized placebo-controlled trials (>1000 patients). We explored whether drug effect on major vascular events changed according to cross-exposure to other drug classes or to cardiovascular risk factors (hypertension or type 2 diabetes), through a meta-analysis of relative odds ratio computed by trial subgroups.
Objective: To construct a sudden death risk score specifically for hypertension (HYSUD) patients with or without cardiovascular history.
Methods: Data were collected from six randomized controlled trials of antihypertensive treatments with 8044 women and 17 604 men differing in age ranges and blood pressure eligibility criteria. In total, 345 sudden deaths (1.
Background And Objectives: Statins showed mixed results in heart failure (HF) patients. The benefits in major HF outcomes, including all-cause mortality and sudden cardiac death (SCD), have always been discordant across systematic reviews and meta-analyses. We intended to systematically identify and appraise the available evidence that evaluated the effectiveness of statins in clinical outcomes for HF patients.
View Article and Find Full Text PDFBackground And Objectives: Sudden cardiac death (SCD) is a severe burden of modern medicine. Aldosterone antagonist is publicized as effective in reducing mortality in patients with heart failure (HF) or post myocardial infarction (MI). Our study aimed to assess the efficacy of AAs on mortality including SCD, hospitalization admission and several common adverse effects.
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