Vitamin B6 Pathway Maintains Glioblastoma Cell Survival in 3D Spheroid Cultures.

Glioblastoma (GBM) is a deadly brain cancer. The prognosis of GBM patients has marginally improved over the last three decades. The response of GBMs to initial treatment is inevitably followed by relapse.

Liposomal Drug Delivery against Using Furazolidone and N-Acetyl Cysteine in Augmented Therapy.

() infection is a significant global health concern, affecting approximately 50% of the world's population and leading to gastric ulcers, gastritis, and gastric cancer. The increase in antibiotic resistance has compromised the efficacy of existing therapeutic regimens, necessitating novel approaches for effective eradication. This study aimed to develop a targeted liposomal drug delivery system incorporating furazolidone and N-acetylcysteine (NAC) to enhance mucopenetration and improve eradication.

Telephone follow-up after early medical abortion using Australia's first low sensitivity urine pregnancy test.

Background: Follow-up after early medical abortion (EMA) in Australia often entails tracking serum human chorionic gonadotropin levels or performing ultrasonography in-clinic. In other countries, methods of follow-up such as using a low-sensitivity urine pregnancy test (LSUPT), telephone evaluation and a questionnaire have been demonstrated to be safe and acceptable.

Aims: To evaluate the safety and efficacy of telephone follow-up after EMA using an LSUPT and questionnaire.

Thyroid cancer risk assessment indicators: A correlation between preoperative and postoperative criteria.

Background And Objectives: To differentiate preoperatively between benign nodule and thyroid cancer (TC) is highly important. Therefore, we investigated the risk assessment indicators that correlate preoperative clinical, radiological, and pathological features with post-operative TC characteristics.

Methods: An observational retrospective study was performed in Bahrain Defense Force (BDF) hospital for all patients suspected of having thyroid cancer from January 2016 to October 2020.

Comparison of cervical cell morphology using two different cytology techniques for early detection of pre-cancerous lesions.

Cervical cancer is an issue of foremost importance globally, specifically affecting the developing nations. Significant advances have taken place with regard to diagnosis of cervical cancer, especially with screening. Appropriate screening measures can thus reduce the incidence of cervical cancer.

Spontaneous osteochondroma resolution in a young female: imaging and histopathological findings.

Objective: To report the first operated and histopathologically studied case of spontaneously resolving solitary osteochondroma.

Case Presentation And Identification: An 18-year-old girl presented with leg pain of 2 months' duration. She had been diagnosed to have a proximal tibial osteochondroma since the age of 9 years.

Incidence of developmental dysplasia of the hip in Dubai.

Objective: To provide a database on the incidence of developmental dysplasia of hip (DDH) among newborns in Dubai, United Arab Emirates (UAE).

Methods: This is a retrospective study of babies born in Dubai Hospital, Dubai, UAE, suspected of having hip dysplasia. Their case records were studied, and the conclusions and treatment were analyzed.

Osteochondroma of the scapula associated with winging and large bursa formation.

Objective: To report a case of scapular osteochondroma associated with pain and winging that is rarely reported in the medical literature.

Case Presentation And Identification: A 19-year-old male presented with pain and winging of the right scapula. CT scan revealed an osteochondroma of the medial border of the scapula with a large bursa between the chest wall and the tumour.

Recurrent stupor due to lysinuric protein intolerance.

Recurrent stupor in children is an uncommon clinical problem with a wide differential diagnosis; inherited metabolic disorders account for a vast majority. We report a 9-year-old girl with recurrent episodes of stupor. Initial episode was treated as viral encephalitis and the second episode was managed as non-convulsive status epilepticus.

A descriptive analysis of South African and Islamic abortion legislation and local Muslim community responses.

The issue of abortion has been the subject of much debate in the recent past in South Africa. Prior to 1996 abortion legislation was punitive and therefore one with which conservative Muslims could identify. Since 1996 the law has been liberalized and replaced by a new Act.

Brainstem abscess complicating tetralogy of Fallot successfully treated with antibiotics alone.

Medically treated brainstem abscess in a 11 year old boy with tetralogy of Fallot is reported. There was a complete resolution of the lesion without any neurologic sequelae during parenteral antibiotic therapy with crystalline penicillin, chloramphenicol and metronidazole. The pathogenesis and management of cardiogenic brain abscesses in general and brainstem abscess in particular has been reviewed.

Role of gastric lavage and broncho-alveolar lavage in the bacteriological diagnosis of childhood pulmonary tuberculosis.

Objective: To compare the mycobacteriological yield from gastric lavage (GL) and bronchoalveolar lavage (BAL), in children with pulmonary tuberculosis.

Methods: 58 consecutive children with chest radiograph suggestive of tuberculosis and positive Mantoux test or a positive history of family contact with a case of tuberculosis were prospectively subjected to gastric lavage on three consecutive mornings and broncho-alveolar lavage on the last day. The samples were subjected to bacteriological isolation.