Synthesis of the quinazolinone derivatives using an acid-functionalized magnetic silica heterogeneous catalyst in terms of green chemistry.

In this research, the synthesis of the quinazolinone derivatives by the reaction of diaminoglyoxime with anthranilic acid or methyl 2-amino benzoate over an acetic acid-functionalized magnetic silica-based catalyst in water was described. The acetic acid-functionalized catalyst was prepared using a three-step procedure from magnetite NPs that initially coated with a layer of silica through the sol-gel process, modified with an aminosilane layer and functionalized with bromoacetic acid. The catalyst was characterized by means of spectroscopic and microscopic techniques, and its activity was investigated for the synthesis of the quinazolinones, bisquinazolinone and oxadiazole quinazolinones obtained from diaminoglyoxime in water at room temperature.

Preparation of Molecularly Imprinted Magnetic Graphene Oxide-Gold Nanocomposite and Its Application to the Design of Electrochemical Sensor for Determination of Epinephrine.

In this study, a new molecularly imprinted polymer (MIP) based nanocomposite was synthesized then used to determine epinephrine (EPN) by the use of an electrochemical sensor modified by it. Typical techniques for the synthesis of MIP have disadvantages, such as weak binding sites, low mass transfer and low selectivity. One of the ways to improve electrochemical properties is the use of graphene oxide (GR-Ox) and modification of its surface.