Visualizing the target estimand in comparative effectiveness studies with multiple treatments.

Comparative effectiveness research using real-world data often involves pairwise propensity score matching to adjust for confounding bias. We show that corresponding treatment effect estimates may have limited external validity, and propose two visualization tools to clarify the target estimand. We conduct a simulation study to demonstrate, with bivariate ellipses and joy plots, that differences in covariate distributions across treatment groups may affect the external validity of treatment effect estimates.

Psychosocial and demographic predictors of quality of life in a large sample of cancer patients.

In recent years, there has been increasing emphasis on understanding how the cancer experience affects individuals' quality of life (QOL). The goal of this study was to assess the QOL and to identify psychosocial predictors of QOL among a large sample of patients with a variety of cancers. Specifically, we assessed the unique contribution of demographic variables, medical variables, and social support on patients' QOL and psychological adjustment.

The food intake recording software system is valid among fourth-grade children.

Objectives: To assess the validity of the Food Intake Recording Software System (FIRSSt) against observation of school lunch and a 24-hour dietary recall (24hDR); and to test the effects of sequencing, observation and a hair sample as a bogus pipeline on accuracy of dietary report.

Design: Six-group design systematically varying sequence of self-report (FIRSSt vs 24hDR), observation of school lunch and hair sample as a bogus pipeline manipulation, with random assignment of participants.

Subjects/setting: 138 fourth-grade students in 2 elementary schools.

Ethnic differences in social correlates of diet.

Little is known about whether culture influences social correlates of dietary behaviors. Questionnaires on parent- and child-reported family and peer influences on children's fruit, juice and vegetable consumption were analyzed for ethnic group differences in responses. Grade 4-6 students completed the questionnaires in the classroom and their parents completed telephone or in-home interviews.

Spit tobacco prevention and cessation counseling: statewide survey of health-care professionals and educators.

The use of spit tobacco (ST) products is a serious public health problem in the United States. Use of ST is associated with increased risk of oral cancer, gastrointestinal neoplasms, and other deleterious effects. The prevalence of ST use among adolescents is high in many areas, especially in predominantly rural states (e.