Publications by authors named "Moonyoung Jang"
Article Synopsis
- Electroconvulsive therapy (ECT) is shown to help patients with treatment-resistant psychosis, yet the exact mechanisms of how it works are still not fully understood.
- This study used MRI texture analysis to investigate microstructural changes in limbic structures after ECT, demonstrating a correlation between these changes and improvement in symptoms, particularly in the left hippocampus and right amygdala.
- The research involved 36 patients undergoing ECT, 27 on medication alone, and 70 healthy controls, providing in vivo evidence supporting the idea that ECT induces neuroplastic changes that may be targeted for future treatments in psychosis.
Article Synopsis
- The study focuses on how adolescents often struggle to recognize depressive symptoms and may not seek help despite experiencing them, highlighting the need for early intervention.* -
- Researchers collected various types of digital data, such as keystroke and stylus information, from 927 first-year middle school students as they completed language and math problems to analyze their depressive symptoms.* -
- The findings suggest that certain digital behaviors (like stroke length and tap pressure) can indicate mood and cognitive issues, pointing toward the possibility of using automated data for early screening of depression in students.*
Patients with mental illnesses, particularly psychosis and obsessive‒compulsive disorder (OCD), frequently exhibit deficits in executive function and visuospatial memory. Traditional assessments, such as the Rey‒Osterrieth Complex Figure Test (RCFT), performed in clinical settings require time and effort. This study aimed to develop a deep learning model using the RCFT and based on eye tracking to detect impaired executive function during visuospatial memory encoding in patients with mental illnesses.
View Article and Find Full Text PDFAim: Obsessive-compulsive disorder (OCD) is a heterogeneous condition characterized by distinct symptom subtypes, each with varying pathophysiologies and treatment responses. Recent research has highlighted the role of the amygdala, a brain region that is central to emotion processing, in these variations. However, the role of amygdala subregions with distinct functions has not yet been fully elucidated.
View Article and Find Full Text PDFObjective: Spatial normalization is an essential process for comparative analyses that heavily depends on the standard brain template used. Brain morphological differences are observed in different populations due to genetic and environmental factors, causing mismatches in regions when the data are normalized to different population templates. Recent studies have indicated differences between Caucasian and East Asian populations as well as within East Asian populations, suggesting the necessity of population-specific brain templates.
View Article and Find Full Text PDFObjective: Obsessive-compulsive disorder (OCD) is a psychiatric condition that causes significant distress and social costs and often follows a chronic course with frequent relapses. Approximately 20% of patients do not respond to medication or cognitive behavioral therapy; gamma knife surgery (GKS) has been proposed as a treatment option for these patients. However, research on GKS for OCD patients is rare.
View Article and Find Full Text PDFArticle Synopsis
- - Awareness and stigma surrounding internet gaming disorder (IGD) hinder early detection, with prevalence varying significantly and recognized as a serious issue that affects young people's academics and mental health.
- - The study aims to identify digital indicators from tablet sensor data to detect IGD early in students, integrating these insights into daily school activities as a mental health screening tool.
- - Analysis revealed that higher IGDS scores correlated with poorer learning outcomes, and five specific digital behaviors were linked to IGD, explaining a notable portion of the variance in IGD scores.
Objective: We aimed to investigate electroencephalographic (EEG) markers of aberrant hyperfocusing, a novel framework of impaired selective attention, in schizophrenia patients by using theta phase-gamma amplitude coupling (TGC).
Methods: Fifty-four schizophrenia patients and 73 healthy controls (HCs) underwent EEG recording during an auditory oddball paradigm. For the standard and target conditions, TGC was calculated using the source signals from 25 brain regions of interest (ROIs) related to attention networks and sensory processing; TGC values were then compared across groups and conditions using two-way analysis of covariance.
Background: There have been conflicting reports on whether conventional verbal fluency measures can predict the prognosis of individuals at clinical high risk (CHR) for psychosis. We aimed to investigate whether verbal fluency task measures that represent semantic processing more directly than conventional measures could be more reliable predictors of later remission in CHR individuals.
Methods: We recruited CHR individuals and healthy controls to participate in a baseline verbal fluency assessment.