Publications by authors named "Moon-Seok Kang"
In this study, changes in bioactive compound contents and the in vitro biological activity of mixed grains, including oats, sorghum, finger millet, adzuki bean, and proso millet, with eight different blending ratios were investigated. The total phenolic compounds and flavonoid contents ranged from 14.43-16.
View Article and Find Full Text PDFPeanut shells, rich in antioxidants, remain underutilized due to limited research. The present study investigated the changes in the functional compound content and skin aging-related enzyme inhibitory activities of peanut shells by electron-beam treatment with different sample states and irradiation doses. In addition, phenolic compounds in the peanut shells were identified and quantified using ultra-performance liquid chromatography with ion mobility mass spectrometry-quadrupole time-of-flight and high-performance liquid chromatography with a photodiode array detector, respectively.
View Article and Find Full Text PDFPeanut (Arachis hypogaea L.) shell, an abundant by-product of peanut production, contains a complex combination of organic compounds, including flavonoids. Changes in the total phenolic content, flavonoid content, antioxidant capacities, and skin aging-related enzyme (tyrosinase, elastase, and collagenase)-inhibitory activities of peanut shell were investigated after treatment in pressure swing reactors under controlled gas conditions using surface dielectric barrier discharge with different plasma (NOx and O3) and temperature (25 and 150 °C) treatments.
View Article and Find Full Text PDFMemory deterioration in Alzheimer's disease (AD) is thought to be underpinned by aberrant amyloid β (Aβ) accumulation, which contributes to synaptic plasticity impairment. Avenanthramide-C (Avn-C), a polyphenol compound found predominantly in oats, has a range of biological properties. Herein, we performed methanolic extraction of the Avns-rich fraction (Fr.
View Article and Find Full Text PDFIn unilateral cleft lip and palate patients, the alar base is displaced inferoposterolaterally due to the depression of the pyriform aperture in the cleft side, and the drooping of the nostril rim is provoked by displacement of the alar base. This study was conducted between May 1998 and December 2012. In total, 82 patients with secondary unilateral cleft lip nasal deformities were treated using alar base augmentation.
View Article and Find Full Text PDFBackground: Few scales are currently available to evaluate changes in hand volume. We aimed to develop a hand grading scale for quantitative assessments of dorsal hand volume with additional consideration of changes in skin texture; to validate and prove the precision and reproducibility of the new scale; and to demonstrate the presence of clinically significant differences between grades on the scale.
Methods: Five experienced plastic surgeons developed the Hand Volume Rating Scale (HVRS) and rated 91 images.
Article Synopsis
- Excessive activation of microglia, which leads to neuroinflammation, contributes to synaptic loss and neuron death, playing a role in neurodegenerative diseases, prompting the exploration of therapeutic strategies that target microglial activation.
- The study investigates dieckol (DEK), a compound from the brown alga Ecklonia cava, and its effects on microglial activation through specific molecular pathways, aiming to clarify its neuroprotective mechanisms.
- Results show that DEK effectively reduces the activation of signaling pathways (ERK, Akt, and NADPH oxidase) involved in microglial function, ultimately protecting neurons from cell death caused by neurotoxic substances released by activated microglia.
Background: Many surgical techniques have been developed to correct blepharoptosis, including the anterior levator resection or advancement, tarsoaponeurectomy, and Fasanella-Servat Müllerectomy. However, to minimize surgical scarring and reduce the postoperative recovery time, the procedure has been developed from a complete incision to a partial incision, which is appealing to patients. To aid the procedural development, this study describes a surgical technique in which the correction of blepharoptosis and a double eyelid fold operation are performed using a buried suture technique during the same operation.
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- Aromatherapy massage is used for stress management and therapeutic purposes in cancer patients, but its biological effects are not well understood.
- A study involved 13 females receiving aromatherapy massage and a control group, focusing on psychological assessments and neurobiological indicators.
- Results showed that aromatherapy massage improved psychological scores, increased plasma BDNF levels, changed brain wave patterns, and reduced salivary cortisol levels, indicating its significant impact on mental and biological health.
Article Synopsis
- The study investigates how the downregulation of A-type K(+) channels (IA channels) affects somatic excitability in young hippocampal neurons during synaptic activity.
- High levels of KCl and glutamate treatment significantly reduced IA channel activity, while blocking NMDA receptors with MK801 negated this reduction, indicating that synaptic activation is crucial for IA channel modulation.
- The findings suggest that synaptic long-term potentiation (LTP) enhances somatic excitability by altering the expression and kinetics of IA channels, which may play a role in memory processes or the development of certain neurological conditions.
Article Synopsis
- Immature hippocampal neurons with high input resistances (R(in)) may be more prone to hyperexcitability and seizures, raising questions about how I(h) channels help protect these neurons.
- The study classified CA1 neurons from young rats based on their action potential firing times and found those firing faster had higher R(in) but also larger I(h) amplitudes.
- Application of a depolarizing stimulus showed that I(h) channels provided neuroprotection specifically in neurons with higher R(in), indicating a crucial role of these channels in preventing excitability in vulnerable neurons.
Nasal dermoid sinus cysts (NDSCs) are rare neoplasms in the median line of the nasofrontal area. Unlike other dermoid cysts, a NDSC can manifest as a cyst, sinus, or fistula, and may extend intracranially. They usually occur as a mass in the median nasofrontal area and may have a pit.
View Article and Find Full Text PDFBackground: The most common complication of latissimus dorsi myocutaneous flap in breast reconstruction is seroma formation in the back. Many clinical studies have shown that fibrin sealant reduces seroma formation. We investigated any statistically significant differences in postoperative drainage and seroma formation when utilizing the fibrin sealant on the site of the latissimus dorsi myocutaneous flap harvested for immediate breast reconstruction after skin-sparing partial mastectomy.
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