Exergy Analysis of Advanced Adsorption Cooling Cycles.

This study conducted an exergy analysis of advanced adsorption cooling cycles. The possible exergy losses were divided into internal losses and external losses, and the exergy losses of each process in three advanced cycles: a mass recovery cycle, heat recovery cycle and combined heat and mass recovery cycle were calculated. A transient two-dimensional numerical model was used to solve the heat and mass transfer kinetics.

Role of flotillins in the endocytosis of GPCR in salivary gland epithelial cells.

Endocytosis has numerous functions in cellular homeostasis. Defects in the endocytic pathway of receptors may lead to dysfunction of salivary gland secretion. Therefore, elucidating the complex mechanisms of endocytosis may facilitate solutions for disease treatment and prevention.

Role of LPA and the Hippo pathway on apoptosis in salivary gland epithelial cells.

Lysophosphatidic acid (LPA) is a bioactive lysophospholipid involved in numerous physiological responses. However, the expression of LPA receptors and the role of the Hippo signaling pathway in epithelial cells have remained elusive. In this experiment, we studied the functional expression of LPA receptors and the associated signaling pathway using reverse transcriptase-PCR, microspectrofluorimetry, western blotting and immunocytochemistry in salivary gland epithelial cells.

Epigenetic modulation of the muscarinic type 3 receptor in salivary epithelial cells.

Muscarinic receptors, particularly the type 3 subtype (M3R), have an important role in exocrine secretion. M3R normally function in HSG cells originated from human submandibular gland ducts, but not in A253 and SGT cells, derived from human submandibular carcinoma and salivary gland adenocarcinoma. However, the underlying mechanism of this suppression has remained elusive.

IRBIT plays an important role in NHE3-mediated pHi regulation in HSG cells.

Expression of inositol-1,4,5-trisphosphate (IP3) receptor-binding protein (IRBIT) has been reported in epithelial cells. However, its role in pHi regulation is not well understood. In this study, we investigated the role of IRBIT in pHi regulation, mediated by Na(+)/H(+) exchangers (NHEs), in salivary glands.