Publications by authors named "Moomin H Bhat"
Article Synopsis
- Pediatric thyroid disorders are increasingly diagnosed, with subclinical hypothyroidism (SCH) being the most common, found in 39% of cases among children referred for evaluation.
- The study involved 241 treatment-naïve children under 18, where data was collected on various thyroid-related metrics, and treatment decisions were made based on clinical judgment with a follow-up over a year.
- Significant factors influencing treatment included age, gender, autoantibody positivity, and family history, indicating that autoimmunity and familial links play essential roles in managing SCH and highlight the need for ongoing surveillance for congenital hypothyroidism (CH).
Objective: Enlargement of the adrenal glands and variable adrenocortical function have been reported in patients with pulmonary tuberculosis and, in a few studies, in patients with extrapulmonary tuberculosis (EPTB). However, none of the studies have evaluated the course of the adrenal morphology in these patients.
Subjects And Methods: Prospective study including 37 patients with EPTB and 37 healthy age- and sex-matched controls.
Background and objective Individuals with prolactinoma exhibit elevated rates of obesity, metabolic syndrome (MS), and dyslipidemia compared to their healthy counterparts. However, there is a lack of data regarding metabolic variance between male and female prolactinoma patients. Consequently, this study aimed to investigate and compare sex-specific discrepancies in metabolic abnormalities among individuals diagnosed with prolactinoma.
View Article and Find Full Text PDFThyroid Autoimmunity and Subclinical Hypothyroidism in Prolactinoma: A Case Control Study.
Indian J Endocrinol Metab
April 2022
Background: This study was aimed at determining the frequency of thyroid autoimmunity and subclinical hypothyroidism in patients with hyperprolactinemia due to prolactinoma compared to well-matched healthy controls.
Methods: This was a cross-sectional study wherein 78 treatment naïve prolactinoma patients and ninety-two healthy control subjects were recruited. Serum prolactin (PRL), thyroid-stimulating hormone (TSH), total thyroxine (T4), circulating anti-thyroid peroxidase (anti-TPO), and anti-thyroglobulin (anti-Tg) antibody levels were measured in all study subjects.
Background: Diabetes has a negative impact on patient's quality of life (QoL). Comorbidities and polypharmacy further worsen their QoL. Thus, in addition to glycemic control, assessment of QoL is also gaining importance.
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- Maturity onset diabetes of young (MODY) is often underdiagnosed but is critical for determining the right treatment and understanding the disease's progression, especially for younger diabetic patients.
- This study analyzed 1,094 young diabetic patients (≤35 years) to assess the prevalence and clinical characteristics of MODY, finding a 7.7% prevalence among the cohort, predominantly affecting males and characterized by leaner body types and early onset.
- The findings highlight the importance of proper diagnosis to avoid mismanagement like unnecessary insulin treatment, which can significantly impact the quality of life and healthcare costs for affected individuals.
Diabetic cardiomyopathy (DCM) pathogenesis is multifarious, and there are insufficient therapeutic options to treat DCM. The present research explored the effects of Citrus grandis peel ethanolic extract (CGPE) in alloxan-induced DCM in rats. Diabetes was triggered by intraperitoneal (i.
View Article and Find Full Text PDFBackground: Obstructive sleep apnea (OSA) occurs in both obese and nonobese individuals. This study was designed to compare clinical, metabolic profile, and polysomnographic parameters among obese and nonobese OSA patients.
Material And Methods: This cross-sectional retro-prospective study involved 148 OSA patients.
Purpose: The lactate level is being increasingly used as a marker of severity of illness and prognosis in multitude of critical conditions. However, its role in diabetic ketoacidosis (DKA) is not well defined.
Aim: To determine the prevalence and clinical importance along with the underlying role of metformin in lactic acidosis (LA) in patients admitted with DKA.
Article Synopsis
- The study investigates the prevalence and significance of asymptomatic bacteriuria (ASB) in patients with type 2 diabetes (T2D) compared to healthy controls, finding ASB more common in T2D patients (17.5% vs. 10%).
- High-risk factors for ASB include being postmenopausal, having a history of urinary tract infections (UTIs), uncontrolled diabetes, and a longer duration of the disease.
- Although ASB increases the risk of symptomatic UTI over time, it does not negatively impact kidney function in T2D patients.
There are scarce data on the prevalence of thyroid disorders and urinary iodine status among tribal populations of India, with no reported data from Kashmir valley. To estimate the prevalence of thyroid disorders and evaluate urinary iodine concentration (UIC) and thyroid autoantibody status among Gujjar and Bakerwal tribes of Kashmir valley. This cross-sectional study recruited tribal subjects using multistage cluster sampling from 5 out of 22 districts of Jammu and Kashmir (J&K).
View Article and Find Full Text PDFBackground: Fibrocalculous pancreatic diabetes (FCPD) is a secondary form of diabetes, described from several tropical countries, including India. We described the existence of this entity in the subtropical region-the Kashmir valley of the Indian subcontinent and compared the clinical characteristics of these patients with type 2 diabetes mellitus (T2DM) patients.
Aim: The present study aimed to compare the clinical characteristics of patients with FCPD and those with T2DM to identify the characteristics distinctive of FCPD.
Purpose: To present the clinical data, investigative profile, and management of patients with disorders of sex development (DSD) from the endocrine unit of a tertiary care university hospital.
Materials And Methods: This retrospective study included 73 cases of DSD, evaluated and managed at Department of Endocrinology, Sher-i-Kashmir Institute of Medical Sciences, Srinagar, Kashmir, over a period of 10 years from September 2008 to August 2018.
Results: Twenty-nine patients (39.
Introduction: The management of acromegaly, a rare and potentially curable disease, has undergone a paradigm shift in the past few decades. Many of the treatment modalities recommended for acromegaly are either too expensive or not available in many parts of India. There is a dearth of treatment and outcome data in Indian patients.
View Article and Find Full Text PDFVitamin D Toxicity: A Prospective Study from a Tertiary Care Centre in Kashmir Valley.
Indian J Endocrinol Metab
January 2019
Background: Vitamin D toxicity (VDT), a "not uncommon" cause of hypercalcemia, can be life-threatening and cause substantial morbidity, if not treated promptly.
Aims: To describe presentation, management, and outcome in 32 patients with VDT diagnosed over 3 years.
Materials And Methods: Patients presenting with VDT at a tertiary care centre in Srinagar Kashmir India were included.
Polycystic ovary syndrome (PCOS), a major endocrinopathy is associated with barrage of metabolic aberrations. Reports in literature on association of PCOS and autoimmunity are conflicting. We aim to evaluate serum levels of anti-nuclear antibody (ANA) among Indian women with PCOS.
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