Publications by authors named "Mookho S Lerata"

Article Synopsis
  • * Researchers extracted three known metabolites and utilized NMR to identify their structures, then loaded these compounds onto gold nanoparticles (sAuNPs) made from brown seaweed extract to improve their targeting capability.
  • * The resulting compound-AuNP conjugates demonstrated over 90% effectiveness in penetrating cancer cells (specifically MCF-7), suggesting that this method may address the challenges faced in developing new anticancer drugs.
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The use of natural products as chemotherapeutic agents is well established; however, many of these are associated with undesirable side effects, including high toxicity and instability. Furthermore, the development of drug resistant cancers makes the search for new anticancer lead compounds a priority. In this study, the extraction of an sp.

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