Publications by authors named "Monzr Almalki"

Article Synopsis
  • Protracted conflict in Syria has devastated the health system, particularly affecting the diagnosis and treatment of high-cost diseases like cancer.
  • A total of 397 new cancer cases were diagnosed in Northwest Syria in 2020, with bladder and breast cancers being the most common among men and women, respectively.
  • This analysis highlights the urgent need for further research and resource allocation to improve cancer care and health systems in conflict zones, emphasizing the lack of support for hospitals and cancer centers under these challenging conditions.
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Plasmablastic lymphoma (PBL) is recognized by the World Health Organization as a very aggressive subtype of non-Hodgkin lymphoma. It was initially described in the setting of human immunodeficiency virus (HIV) infection, but it has since been identified in immunocompetent patients, as well. PBL is characterized by CD20 negativity and is associated with Epstein-Barr virus infection.

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Impairing dendritic cell (DC) function to prevent graft versus host disease (GvHD) is an appealing concept. DC antigen presentation is NF-κB pathway-dependent and bortezomib might therefore play a role in preventing alloreactivity. We obtained DC from the blood of patients enrolled in a phase I study using post-transplant cyclophosphamide and bortezomib for prevention of GvHD.

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