Publications by authors named "Monya Todesco Bernasconi"
Objective: To evaluate the predictability of gestational diabetes mellitus wth a 75 g oral glucose tolerance test (OGTT) in early pregnancy, based on the 2013 criteria of the World Health Organization, and to test newly proposed cut-off values.
Design: International, prospective, multicentre cohort study.
Setting: Six university or cantonal departments in Austria, Germany, and Switzerland, from 1 May 2016 to 31 January 2019.
Objectives: This study aimed to evaluate the risk of congenital malformation among pregnant women exposed to the mRNA COVID-19 vaccines during the first trimester of pregnancy, which is a developmental period where the foetus is at risk of teratogenicity.
Methods: Pregnant women were prospectively enrolled from March 2021 to March 2022, at the time of COVID-19 vaccination. Pregnant women exposed to at least one dose of mRNA COVID-19 vaccine from conception to 11 weeks of gestations and 6 days were compared with pregnant women exposed to the vaccine from 12 weeks to the end of pregnancy.
Maternal and perinatal outcomes following pre-Delta, Delta, and Omicron SARS-CoV-2 variants infection among unvaccinated pregnant women in France and Switzerland: a prospective cohort study using the COVI-PREG registry.
Lancet Reg Health Eur
March 2023
Article Synopsis
- SARS-CoV-2 positive pregnant women have a varying risk of severe maternal adverse outcomes depending on the circulating variant, with higher risks during the Delta variant wave.
- A study of 2055 unvaccinated pregnant women from March 2020 to September 2022 showed 3.4% had severe outcomes in the pre-Delta period, increasing to 6.5% during Delta, and decreasing to 1.0% during Omicron.
- The study also highlighted that pregnancy complications were common across all periods, with stillbirth rates rising significantly during the Delta wave.
Article Synopsis
- - The study investigates the safety of mRNA COVID-19 vaccines in pregnant women in Switzerland, focusing on adverse events and pregnancy outcomes after vaccination from March to December 2021.
- - Among 1,012 vaccinated women, most reported local pain after shots, but severe adverse events were rare, with only four reported cases (0.4%) including pulmonary embolism and fever.
- - Notably, the rates of spontaneous abortions and stillbirths were low, and while some women delivered preterm, no stillbirths occurred among those vaccinated during pregnancy.
Pituitary apoplexy is caused by haemorrhage or infarction of the pituitary gland. Presenting signs and symptoms often include severe headache, visual disturbance, ophthalmoplegia, altered consciousness and impaired pituitary function. The management of pituitary apoplexy has very rarely been described during pregnancy and there is no existing data for further pregnancies of affected women.
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- * A study involving 926 pregnant women revealed that 9.9% had severe COVID-19, with risk factors including pulmonary issues, hypertension, and diabetes.
- * Severe maternal illness was linked to higher rates of cesarean sections, preterm deliveries, and neonatal admissions to intensive care units.
Background: One of the major complications related to delivery is labor dystocia, or an arrested labor progress. Many dystocic deliveries end vaginally after administration of oxytocin, but a large numbers of women with labor dystocia will undergo a long and unsafe parturition. As a result of the exertion required in labor, the uterus produces lactate.
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