Topical dorzolamide for macular holes: A randomised, double-blind, placebo-controlled trial.

Background: To assess topical dorzolamide as medical therapy for idiopathic full-thickness macular holes (FTMHs).

Methods: Randomised, double-blinded, placebo-controlled, single-centre clinical trial involving 32 patients with idiopathic small FTMHs (<400 ). Participants in both arms used topical dorzolamide 2% or saline thrice daily for 8 weeks with monthly OCT.