Publications by authors named "Montse Fernandez Guarino"

Hailey-Hailey disease (HHD) is a rare genodermatosis that is often difficult to treat. This paper reports three patients with HHD treated with one session of photodynamic therapy (PDT) using topical methyl aminolevulinic acid applied under occlusion for 3 hours and red light at 37 J/cm2 for 7.5 minutes.

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Introduction: Phakomatosis pigmentovascularis (PPV) is a rare syndrome characterized by the association of a vascular nevus with an extensive pigmentary nevus.

Objective: We sought to study and evaluate clinical findings in patients with PPV referred to the laser department of our hospital.

Methods: We revised the clinical findings of 15 patients with PPV and reclassified them according to Happle's new classification.

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Article Synopsis
  • Epidermal growth factor inhibitors (EGFR) are cancer treatments that often cause acneiform rashes, and while many topical and systemic treatments are noted, none have clear evidence of effectiveness.
  • A study involving 6 patients treated with 100 mg of doxycycline daily showed promising results, with 5 patients achieving complete resolution of their rashes in 3 weeks.
  • The findings suggest doxycycline could be an effective treatment for EGFR-induced rashes, supporting its use based on the positive outcomes observed in this small study.
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Gefitinib (Iressa) is a new antineoplastic agent that acts by selectively inhibiting epidermal growth factor receptor tyrosine kinase (EGFR-TK). It has shown activity against several solid tumors. Because of their action mechanism, gefitinib and other tyrosine kinase inhibitors have been associated with multiple cutaneous effects, most of which are mild and well tolerated.

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