Publications by authors named "Montero-Perez-Barquero M"
Background: Patients with heart failure (HF) and chronic obstructive pulmonary disease (COPD) have a high risk of hospital admission and mortality. This study evaluated the benefit of a care model, characterized by comprehensive and continuous care (UMIPIC program) in patients with HF and a history of COPD.
Methods: A total of 5644 patients were prospectively recruited, of which 1320 had a history of COPD between March 2008 and March 2020.
Heart failure (HF) with preserved ejection fraction (pEF) has lacked effective treatments for reducing mortality. However, previous studies have found an association between statin use and decreased mortality in patients with HFpEF. The aim of this study was to analyse whether statin therapy is associated with a reduction in mortality in these patients and whether the effect differs according to the presence or absence of ischaemic heart disease (IHD).
View Article and Find Full Text PDFBackground And Objective: Heart failure (HF) is a syndrome of epidemic proportions and one of the main reasons for hospital admission. Patient registries provide real-world clinical practice information which is complementary to clinical trials. RICA-2 is a registry of the Spanish Society of Internal Medicine.
View Article and Find Full Text PDFObjective: Two profiles of patients with heart failure with preserved ejection fraction (HFpEF) and type 2 diabetes mellitus (T2DM) can be discerned: those with ischemic and those with diabetic cardiomyopathy (DMC). We aim to analyze clinical differences and prognosis between patients of these two profiles.
Material And Methods: This cohort study analyzes data from the Spanish Heart Failure Registry, a multicenter, prospective registry that enrolled patients admitted for decompensated heart failure and followed them for one year.
Article Synopsis
- Patients with heart failure (HF) and cardiorenal syndrome (CRS) face challenges like higher hospital stays and mortality rates due to their age and health issues.
- The UMIPIC program, involving specialized care from internists and nurses, was studied to see if it could improve outcomes for these patients.
- Results showed that those in the UMIPIC program had significantly fewer hospital readmissions (20% vs 32%) and lower mortality rates (24% vs 36%) compared to those receiving standard care, indicating its effectiveness in providing better long-term management.
Background: Patients with chronic diseases such as heart failure (HF) are at risk of hospital admission. We evaluated the impact of living in nursing homes (NH) on readmissions and all-cause mortality of HF patients during a one-year follow up.
Methods: An observational and multicenter study from the Spanish National Registry of Heart Failure (RICA) was performed.
Introduction: Patients with diabetes mellitus (DM) and heart failure (HF) have a worse prognosis despite therapeutic advances in both diseases. Sodium-glucose co-transporter type 2 and GLP-1 receptor agonists have shown cardiovascular benefits and they have been positioned as the first step in the treatment of DM in patients with HF or high cardiovascular risk. However, in the pivotal trials the majority of patients receive concomitant treatment with metformin.
View Article and Find Full Text PDFTo estimate the projected effectiveness of dapagliflozin in subjects with heart failure (HF) with reduced ejection fraction in clinical practice in Spain. This multicenter cohort study included subjects aged 50 years or older consecutively hospitalized for HF in internal medicine departments in Spain. The projected clinical benefits of dapagliflozin were estimated based on results from the DAPA-HF trial.
View Article and Find Full Text PDFArticle Synopsis
- A multicenter study in Spain examined the potential benefits of dapagliflozin for patients with heart failure (HF) with mildly reduced or preserved ejection fraction.
- Out of 4049 patients over 50 years old, 80.8% met the criteria for dapagliflozin treatment, with significant rates of rehospitalization (22.2%) and mortality (21.6%) within a year after discharge.
- The use of dapagliflozin is projected to reduce the absolute risk of mortality by 1.3% and HF readmissions by 5.1%, indicating a potential to lessen the burden of HF in these patients.
To determine the projected benefits of dapagliflozin after an acute heart failure (HF) event in Spain. A multicenter and prospective study that included subjects aged 50 years or older consecutively admitted with HF to internal medicine departments in Spain. The projected clinical benefits of dapagliflozin were calculated pooled analysis of the DAPA-HF and DELIVER trials.
View Article and Find Full Text PDFObjective: To investigate the association of corrected QT (QTc) interval duration and short-term outcomes in patients with acute heart failure (AHF).
Methods: We analyzed AHF patients enrolled in 11 Spanish emergency departments (ED) for whom an ECG with QTc measurement was available. Patients with pace-maker rhythm were excluded.
Background And Aims: The prognostic role of pulse pressure (PP) in heart failure (HF) patients with preserved left ventricular ejection fraction (LVEF) is not well understood. Our aim was to evaluate it in acute and stable HF.
Material And Methods: This work is a retrospective observational study of patients included in the RICA registry between 2008 and 2021.
Objective: The role of comorbidities in heart failure (HF) outcome has been previously investigated, although mostly individually. We investigated the individual effect of 13 comorbidities on HF prognosis and looked for differences according to left-ventricular ejection fraction (LVEF), classified as reduced (HFrEF), mildly-reduced (HFmrEF) and preserved (HFpEF).
Methods: We included patients from the EAHFE and RICA registries and analysed the following comorbidities: hypertension, dyslipidaemia, diabetes mellitus (DM), atrial fibrillation (AF), coronary artery disease (CAD), chronic kidney disease (CKD), chronic obstructive pulmonary disease (COPD), heart valve disease (HVD), cerebrovascular disease (CVD), neoplasia, peripheral artery disease (PAD), dementia and liver cirrhosis (LC).
Effectiveness of sacubitril-varsartan versus angiotensin converting enzyme inhibitors in patients hospitalized for acute heart failure: a retrospective cohort study of the RICA registry.
J Geriatr Cardiol
November 2022
Article Synopsis
- Sacubitril-valsartan has been shown to lower hospitalizations and death rates in heart failure patients, but there is limited real-world data on its effectiveness in older patients.
- A study was conducted using a Spanish heart failure registry to compare elderly patients treated with sacubitril-valsartan versus those on angiotensin converting enzyme inhibitors (ACEI) during acute heart failure hospitalization.
- Results indicated that while sacubitril-valsartan was associated with a trend towards fewer readmissions and deaths due to heart failure compared to ACEI, these findings were not statistically significant over follow-up periods of 3 months and 1 year.
Introduction: Beta-adrenergic receptor blockers (beta-blockers) are frequently used for patients with heart failure (HF) with preserved ejection fraction (HFpEF), although evidence-based recommendations for this indication are still lacking. Our goal was to assess which clinical factors are associated with the prescription of beta-blockers in patients discharged after an episode of HFpEF decompensation, and the clinical outcomes of these patients.
Methods: We assessed 1078 patients with HFpEF and in sinus rhythm who had experienced an acute HF episode to explore whether prescription of beta-blockers on discharge was associated with one-year all-cause mortality or the composite endpoint of one-year all-cause death or HF readmission.
Article Synopsis
- This study investigates the impact of different types of caregivers on heart failure (HF) patients, focusing on characteristics, hospital admissions, and mortality rates.
- Conducted on 2,147 patients from a national registry, it categorizes caregivers into four groups: self-care, partners, children, and professional caregivers.
- Results reveal that while there were no significant differences in readmission or mortality rates among the caregiver groups, women tended to have children or professional caregivers, while men often cared for themselves or had spouses as caregivers.
Article Synopsis
- Heart failure (HF) is common in older adults and often worsened by other health issues; this study analyzed data from a national registry of HF patients aged 50 and over.
- Out of 5424 patients, a significant 61% died within a year, with mortality rates increasing as the PROFUND index score (a measure of health risk) rose; those with scores above 11 had the highest risk.
- The findings suggest that the PROFUND index is effective in predicting one-year mortality for HF patients, particularly beneficial for identifying those at intermediate to high risk.
Objectives: This work aims to determine the prevalence, characteristics, and impact on prognosis of right bundle branch block (RBBB) in a cohort of acute heart failure (AHF) patients.
Methods: We prospectively analyzed 3,638 AHF patients included in the RICA registry (National Heart Failure Registry of the Spanish Internal Medicine Society). We independently analyzed the relationship between baseline and clinical characteristics and the presence of RBBB as well as the potential impact of RBBB on 1-year all-cause mortality and a composite endpoint of 90-day post-discharge hospitalization or death.
Background: Carbohydrate antigen 125 (CA125) has emerged as a new biomarker in heart failure. The objective of the study is to determine whether serum CA125 levels predict total mortality and readmissions at one year in patients >70 years old with acute heart failure (AHF) and preserved ejection fraction (PEF).
Methods: Multicenter prospective observational study, which included 359 patients (mean age 81.
Aims: Heart failure (HF) and diabetes are 2 strongly associated diseases. The main objective of this work was to analyze changes in the prognosis of patients with diabetes who were admitted for heart failure in 2 time periods.
Methods: This work is a prospective study comparing prognosis at one year of follow-up among patients with diabetes who were hospitalized for HF in either 2008-2011 or 2018.
Background: Elderly patients with heart failure (HF) have a high degree of comorbidity which leads to fragmented care, with frequent hospitalizations and high mortality. This study evaluated the benefit of a comprehensive continuous care model (UMIPIC program) in elderly HF patients.
Methods And Results: We prospectively analyzed data from the RICA registry on 2862 patients with HF treated in internal medicine departments.
Introduction: Ambulatory blood pressure monitoring (ABPM) has demonstrated value in the prognostic assessment of hypertensive patients with heart failure (HF) with or without other cardiovascular diseases. The objective of this study was to evaluate whether ABPM can identify subjects with HF with a worse prognosis.
Methods And Results: Prospective multicenter study that included clinically stable outpatients with HF.
Objective: To assess whether a sustained optimal haemoglobin value in the 3 months after admission for heart failure (HF) decompensation reduces morbidity and mortality during the 12 months after admission for acute HF.
Patients And Method: Retrospective study of the 1408 patients older than 65 years included in the RICA registry divided into 3 groups: no anaemia (group A), recovered anaemia (group B), and persistent anaemia (group C), according to haemoglobin levels on admission, and 3 months after discharge. Kaplan-Meier curves were constructed, comparing the groups using the log-rank test and a Cox regression model was performed to analyse survival.
Introduction: There are few data in the Spanish population about the causes of death in patients admitted to internal medicine departments for heart failure. Their study according to left ventricular ejection fraction (reduced: rEF, mid-range: mEF, and preserved: pEF) could improve the knowledge of patients and their prognosis.
Methods: Prospective multicentre cohort study of 4144 patients admitted with heart failure to internal medicine departments.