Impact of -acetyl-l-cysteine on SARS-CoV-2 pneumonia and its sequelae: results from a large cohort study.

https://bit.ly/3l1QsVo.

Feasibility and clinical impact of a portable bi-level ventilation device in patients with severe chronic obstructive pulmonary disease and exertional dyspnea: preliminary results from a clinical series.

Unlabelled: We explore home use of a portable bi-level ventilation device among patients with severe chronic obstructive pulmonary disease (COPD), and describe changes in the patients' physical activity levels, perceived dyspnea, anxiety and depression, as well as their satisfaction with the device, after one month of use.

Methods: Forty patients with severe COPD and exertional dyspnea were instructed to use VitaBreath® device (Philips, Respironics) during efforts or activities of daily living for 4 weeks, and agreed to answer questionnaires on anxiety, depression, dyspnea and physical activity.

Results: Twenty-six (65%) patients used the VitaBreath® device for four weeks, while 14 patients (35%) stopped early for various reasons.

Assessment of distribution of CD34 epitope classes in fresh and cryopreserved peripheral blood progenitor cells and acute myeloid leukemic blasts.

Background And Objective: So far several reports have described changes in the expression of surface antigens in progenitor cells and blasts following cryopreservation. However, there are no data on the effects of cryopreservation on the expression of the three CD34 epitope classes, and on their relationship with the clonogenic capacity of PBPC collected by leukapheresis.

Design And Methods: In order to analyze the effects of freezing/thawing procedures (Eth 80C storage for 3 months) and use of dimethylsulfoxide (DMSO) on the immunophenotype profile and colony production of peripheral blood progenitor cells (PBPC) in apheresis products derived from 20 patients with stage 0-III non-Hodgkin's lymphoma (nHL), a flow cytometry study was undertaken using different CD34 monoclonal antibodies (MoAbs) capable of recognizing the 3 epitope classes of CD34 molecule (class III: HPCA-2/FITC, HPCA-2/PE, 581/FITC, 581/PE; class II: Q-Bend 10/PE; class I: ICH3/PE, BI3C5-PE, Immu-133-PE).

[A case of pseudomembranous colitis in childhood].

"Pseudomembranous colitis" is a disease which has gained importance in the last decades. It is caused by intestinal colonization by "Clostridium Difficilis" which in normal situations, especially in the evolutive age, is a component of the normal saprophytic flora. Antibiotic therapy, or reduction of the immunological defenses by surgical procedures, infections, weakening diseases or malnutrition states may produce an alteration of the intestinal flora with a prevalence of Clostridium Difficilis which causes, with its intestinal toxin, organic and functional damages.

[Benign intracranial hypertension during treatment with acetylsalicylic acid: presentation of 2 cases in children].

The authors report two cases of benign intracranial hypertension associated to Aspirin therapy promptly regressed after withdrawal of the drug. This side effect did never described and its pathogenetic mechanism is unknown.

[Sjogren-Larsson syndrome. Description of a case].

The authors describe a typical case of Sjogren-Larsson Syndrome showing a clear improvement of the spastic paresis after 2 years of physiotherapy and a diet rich in polyunsaturated fatty acids.

[Mixed connective tissue disease in childhood. Report of a case].

The Authors report a case of MCTD in a 11 years old girl. Initially the disease presented the classical clinical picture of IDM. Successively its evolution was marked by the appearance of the typical clinical features of JRA, SS and of serum antibodies anti-RNP and by absence of antibodies anti-dsDNA and anti-Sm.

[Mucha-Habermann disease. Description of a case in childhood].

The authors report a case of Mucha-Habermann disease in childhood. Mucha-Habermann disease is not a very well known, though not infrequent, disease. It is characterized by recurrent erythematous-papular-vesicular skin lesions associated with arthralgia or arthritis or large joints.