Italian pediatric intensive care units admitting critically ill cancer children: results from a national survey.

Background: Pediatric patients affected by oncologic disease have a significant risk of clinical deterioration that requires admission to the intensive care unit. This study reported the results of a national survey describing the characteristics of Italian onco-hematological units (OHUs) and pediatric intensive care units (PICUs) that admit pediatric patients, focusing on the high-complexity treatments available before PICU admission, and evaluating the approach to the end-of-life (EOL) when cared in a PICU setting.

Methods: A web-based electronic survey has been performed in April 2021, involving all Italian PICUs admitting pediatric patients with cancer participating in the study.

Impact of breast cancer screening in a population with high spontaneous coverage with mammography.

Objective: The impact of organized screening programs on breast cancer (BC) mortality is unclear in an era of high spontaneous referral of women to mammography. The aim of this study was to analyze if the introduction of mammographic screening programs reduced BC mortality in the Veneto region, Italy, despite already widespread spontaneous access to mammography.

Methods: In Veneto, screening was introduced in different years between 1999 and 2009 across 21 local health units (LHUs), inviting asymptomatic women aged 50-69 years to undergo mammography biennially.

Long-term performance of colorectal cancerscreening programmes based on the faecal immunochemical test.

Background: The long-term performance of colorectal cancer (CRC) screening programmes based on a 2-year faecal immunochemical test (FIT) is still unclear.

Methods: In a sample of 50 to 69-year-olds repeatedly screened with the FIT (OC-Hemodia latex agglutination test; cut-off: 20 µg haemoglobin/g faeces), we examined: (1) the FIT positivity rate, the CRC and advanced adenoma detection rate and the FIT's positive predictive value (PPV) for advanced neoplasia, at each round of screening and (2) the cumulative CRC and advanced adenoma detection rate after five rounds of FIT.

Results: Over 12 years (2002-2014), 123 347 individuals were administered the FIT up to six times, and 781 CRCs and 4713 advanced adenomas were diagnosed.

High sensitivity of five colorectal screening programmes with faecal immunochemical test in the Veneto Region, Italy.

Objective: Although guaiac-based faecal occult blood test screening has been shown to be effective in reducing colorectal cancer (CRC) mortality, it has been criticised mostly for its low sensitivity. Italian CRC screening programmes are based on immunochemical tests (iFOBT). We collected and analysed the interval cancers (ICs) found by five screening programmes to estimate their sensitivity.

[Gastric metastasis of cutaneous melanoma. Apropos of a case letter].

We report a case operated for gastric metastasis of a cutaneous melanoma. Although such localizations are frequent, symptomatology is nonspecific. Diagnostic fibroscopy is effective if the lesion is blackened by melanin.

[Association of bronchogenic cyst of the pancreas and duplication cyst of the stomach].

One case of bronchogenic cyst of the pancreas associated to a true gastric cyst produced by duplication is described. Such congenital neoformations are extremely rare. The symptoms are highly variable.

[Neurologic risks caused by perinatal and neonatal problems in a provincial hospital].

The study intends to value results of follow-up of risk neonates hospitalized for the period 1980-88 at Neonatal Intensive Care Unit of Bufalini Hospital Cesena and the course with time of neurologic and neuropsychological alterations, reported to the birth-rate of territory in which operates the Neonatal Intensive Care Unit. The survivor infants attended in follow up have been 419: 63 of neonatal weight less than or equal to 1500 g (group A), 117 of weight 1501-2000 g (group B), 239 of weight greater than 2000 g (group C). The follow-up provided at first 12 months of life a pediatric examination together with motoscopic examination to Milani-Comparetti every two months, at 3 years--4 years and 6 months, 7 years a pediatric examination with evaluation of Intelligence Quotient (N.

Juvenile pilocytic astrocytoma of the optic nerve diagnosed by fine needle aspiration biopsy.

Fine needle aspiration biopsy of an orbital mass was performed under CT guidance in a nine-year-old boy presenting with rapidly increasing proptosis of the right eye with lateral displacement and no light perception. The cytologic findings consisted of bipolar astrocytes with cytoplasmic fibrillated processes intermingled with Rosenthal fibers. A cytologic diagnosis of juvenile pilocytic astrocytoma was advanced; this was confirmed by subsequent histologic study of the surgical specimen.

[An intra-oral device for orojejunal feeding of low-weight neonates].

An intraoral device has been experimented to stabilize oro-gastric or oro-jejunal feeding tubes in low birth weight newborns.

[Juvenile hyaline fibromatosis. Description of a case and review of the literature].

The authors report a typical case of JHF. The complete review of the literature shows that no more than 20 cases have been so far described. The clinical, pathological and electron microscopic features are stressed and the main clinical and pathological differential diagnoses are considered.

Long-term survival in response to combined chemotherapy and radiotherapy in laryngeal small cell carcinoma.

Fourteen patients with small cell carcinoma of the larynx are studied. This represents the largest series, from a single institution, reported in the literature. This neoplasm is usually highly aggressive and the prognosis very poor, but, in our experience, combined chemo- and radiotherapy can significantly improve the clinical course of the disease.

Analysis of spontaneous deletion mutants of satellite bacteriophage P4.

Spontaneous deletion mutants of satellite bacteriophage P4 have been isolated and characterized. All of the deletions analyzed that were between 850 and 1,700 base pairs long are within the region nonessential for P4 lytic development; some of them cover the cII or the gop locus.

Chondrosarcoma of the larynx: review of the literature and report of three cases.

Three patients with laryngeal chondrosarcoma were observed at the ENT Department of Padua University from 1966 to 1983. Including the present observations, about 150 of these neoplasms have been described in the literature. The male to female ratio was 3:1, and the age at diagnosis ranged from 33 to 91 years (median, 66 years).

Chondromyxoid fibroma of the iliac bone: a case report with ultrastructural observations.

Ultrastructural findings in an unusual case of chondromyxoid fibroma are reported. The tumor was located in the iliac bone of a 42-year-old woman with left hip pain of 5 years duration.

Mucoid carcinoma of the breast on fine-needle aspiration biopsy sample: cytology and ultrastructure.

16 cases of mucoid carcinoma of the breast were diagnosed in specimens obtained by fine-needle aspiration biopsy. The subsequent tissue examination confirmed the cytologic diagnosis in all 16 cases but revealed in 1 case an association with an endocrine component and in 3 cases the presence of an invasive ductal component. The diagnostic and prognostic necessity of distinguishing pure forms of mucoid carcinoma from those associated with invasive ductal carcinoma or endocrine differentiation means that investigations other than fine-needle aspiration biopsy are also required.

[Fat necrosis in the newborn infant associated with hypercalcemia and dyslipidemia (description of a case)].

A case of subcutaneous fat necrosis (S.F.N.