[Squamous cell carcinoma of the penis: treatment protocol according to our 14 years of experience].

Objective: The management of lymph nodes and the determination of prognostic factors are matters of controversy in the treatment of squamous cell carcinoma of the penis. We attempted to establish an approach based on the different types of lymphadenectomies and biopsies we have performed and to evaluate local stage and grade of cellular differentiation as prognostic factors.

Methods: 81 cases treated at our institution between 1980 and 1994 were reviewed.

Consideration of genetic factors in cerebral palsy.

Sixty-two patients with cerebral palsy seen consecutively in a pediatric neurology practice were submitted to a prospective protocol which tabulated their neurological findings, birth and developmental histories and an extensive neurodevelopmental pedigree. Their family histories were compared with those of three control groups, consisting of 62 children with headaches, 62 with school/behavior problems and 62 random normal children. The family histories of the cerebral-palsied children revealed an unusual number of relatives with cerebral palsy, mental retardation and seizures.

Pulmonary amyloidosis: ultrastructural study of early alveolar septal deposits.

A 65-year-old man had tracheobronchial amyloid deposits with osseous metaplasia and amyloid tumors in the lungs, associated with systemic secondary amyloid. Focal alveolar involvement was demonstrated by light microscopy, whereas early deposits, not visible optically, were detected by electron microscopy as focal widening of the basal membrane. The relationship of tracheobronchial amyloidosis to tracheobronchopathia osteoplastica and the similarities between the early pulmonary deposits and those of kidney and thyroid are briefly discussed.

Surgical treatment for chest pain in mitral valve prolapse.

The case of a 40-year-old woman with mitral valve prolapse and severe atypical chest pain is presented. The diagnosis was confirmed by phonocardiographic, echocardiographic, and angiocardiographic studies. The electrocardiogram revealed an ischemic pattern of ST-T on the anterior and inferior wall.

[Down's dyndrome and congenital heart disease (author's transl)].

Out of a group of 113 cases of Down's syndrome 50 were associated with congenital heart disease, confirmed by haemodynamic, angiographic and surgical means. The mean age was 36.6 months.