NHC stabilized copper nanoparticles reduction of a copper NHC complex.

The bottom-up synthesis of plasmonic NHC@CuNPs from common starting reagents, the formation of the synthetically accessible NHC-Cu(I)-Br complex and its reduction by NH·BH is reported. The resulting NHC@CuNPs have been characterized in detail by XPS, TEM and NMR spectroscopy. The stability of NHC@CuNPs was investigated under both inert and ambient conditions using UV-Vis analysis.

Biguanide-Based Synthesis of 1,3,5-Triazine Derivatives with Anticancer Activity and 1,3,5-Triazine Incorporated Calcium Citrate Nanoparticles.

Twelve derivatives of biguanide-derived 1,3,5-triazines, a promising class of anticancer agent, were synthesised and evaluated for their anticancer activity against two colorectal cancer cell lines-HCT116 and SW620. and which are the derivatives containing -hydroxyphenyl substituents exhibited the highest activity with IC against both cell lines in the range of 20-27 µM, which is comparable to the IC of cisplatin reference. Moreover, the potential use of the calcium citrate nanoparticles (CaCit NPs) as a platform for drug delivery system was studied on a selected 1,3,5-triazine derivative .