Publications by authors named "MonishaRita Jayaraman"

E-cadherin is a cell adhesion molecule crucial for maintaining cellular integrity and survival. E-cadherin is the focus of this study, which aims to evaluate its immunohistochemical staining patterns in endometrial carcinoma (EC). Material and methods In this retrospective study, 25 formalin-fixed, paraffin-embedded tissue blocks of EC were retrieved from the Department of Pathology at Saveetha Medical College.

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Article Synopsis
  • Phyllodes tumors (PTs) are rare breast tumors that vary in severity from benign growths (like fibroadenomas) to malignant forms, complicating diagnosis and treatment.
  • Malignant PTs have a high chance of recurrence and poor outcomes, underscoring the need for careful histopathological evaluation and genetic research to improve diagnosis and potential therapies.
  • The article discusses a case of malignant PT in a 74-year-old woman, highlighting the tumor's ability to mimic other types of breast cancer and the important role of immunohistochemistry in accurately diagnosing these tumors.
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The hobnail variant of papillary thyroid carcinoma (HVPTC) represents a distinctive and relatively rare histological subtype of thyroid malignancies. This variant is characterized by its unique cellular morphology with a hobnail appearance, that is, cells with apically positioned nuclei. There are other characteristics like micropapillary pattern and loss of cohesiveness of cells, which are indicative of HVPTC.

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The development of pleural effusion in chronic myeloid leukemia (CML) is not well-understood and rarely documented in literature. Extramedullary involvement (EMI), which occurs in about 10% of CML cases, typically affects lymph nodes and the spleen. Instances of extensive infiltration of leukemic cells into the pleura are infrequently reported in CML.

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