Comparative study on alginate/chitosan microcapsules and Montanide ISA 61 as vaccine adjuvants in mice.

Selection of adjuvant to be combined with the antigen is an extremely important point for formulating effective vaccines. The aim of this study was to evaluate reactogenicity, levels of IgM, IgG and subclasses (IgG1, IgG2b and IgG3), and protection elicited by vaccine formulations with association of chitosan coated alginate or Montanide ISA 61 with γ-irradiated Brucella ovis. The alginate/chitosan biopolymers as well as the Montanide ISA 61 emulsion elicited intense and long-lasting local response, especially when associated with the antigen.

Antigenic and molecular evidence of sp.-associated epididymo-orchitis in frugivorous () and nectarivorous () bats in Brazil.

This study included 47 free-ranging bats from the State of Minas Gerais, Brazil. Six bats (12.8%) had genital inflammatory lesions, and two of them (one and one , a frugivorous and a nectarivorous, respectively) were diagnosed with sp.

The association between obesity, health service use, and work productivity in Australia: a cross-sectional quantile regression analysis.

The burden of disease attributable to obesity is rapidly increasing and becoming a public health challenge globally. Using a nationally representative sample in Australia, this study aims to examine the association of obesity with healthcare service use and work productivity across outcome distributions. We used Household, Income and Labour Dynamics Australia (HILDA) Wave 17 (2017-2018), including 11,211 participants aged between 20 and 65 years.

Promising onychomycosis treatment with hypericin-mediated photodynamic therapy: Case reports.

Background: Onychomycosis (OM) is a common nail plate disorder caused by dermatophyte molds, yeasts, and non-dermatophyte molds, which use keratin in the nail plate as an energy source. OM is characterized by dyschromia, increased nail thickness, subungual hyperkeratosis, and onychodystrophy, and is typically treated with conventional antifungals despite frequent reports of toxicity, fungal resistance, and OM recurrence. Photodynamic therapy (PDT) with hypericin (Hyp) as a photosensitizer (PS) stands out as a promising therapeutic modality.

Performance of Two Extracts Derived from Propolis on Mature Biofilm Produced by .

Species of the genus represent the third most common cause of onychomycosis, the most frequent and difficult to treat nail infection. Onychomycosis has been attributed to fungi organized in biofilm and some natural products have proved promising for its treatment. This study aimed to evaluate the antibiofilm activity of propolis extract (PE) and its by-product (WPE) on 7-day preformed biofilms produced by in polystyrene microplates, as well as in an ex vivo model on human nail fragments.

Chronic oil spills revealed by the most important set of samples from the incident in northeastern Brazil, 2019.

In 2019, an oil spill of unprecedented dimensions and unknown source reached the Brazilian coast. Such incident, which occurred somewhere in the ocean and was detected only when the first oil patches reached the beaches in the northeastern region, is recognized as one of the most serious oil spills in the country. From the chromatographic analysis of the oily residues using n-alkanes, polycyclic aromatic hydrocarbons (PAH), and oil biomarkers, it was possible to characterize their coverage.

Identification and phytoremediation potential of spontaneous species in vineyard soils contaminated with copper.

Copper (Cu) contents in vineyard soils due to the application of cupric fungicides cause changes in the native covering flora. Under these conditions, the surviving individuals accumulate the metal in and decrease its availability in the soil, reducing the potential toxicity to grapevine. We have identified spontaneous plant species and their phytoremediation potential from vineyards of Isabella () on two distinct soil types (Inceptisol and Entisol) contaminated with Cu.

Exploratory and discriminant analysis of plant phenolic profiles obtained by UV-vis scanning spectroscopy.

Some species of cover crops produce phenolic compounds with allelopathic potential. The use of math, statistical and computational tools to analyze data obtained with spectrophotometry can assist in the chemical profile discrimination to choose which species and cultivation are the best for weed management purposes. The aim of this study was to perform exploratory and discriminant analysis using R package specmine on the phenolic profile of L.

Studies of the early stages of the dynamic setting process of chemically activated restorative glass-ionomer cements.

Objective: To evaluate the early stages of the setting process of chemically activated restorative glass-ionomer cements (GICs).

Material And Methods: Five GICs were evaluated ( = 5): Equia Forte (GC), Equia Forte HT (GC), Ketac Universal (3M ESPE), Maxxion R (FGM) and Riva Self Cure (SDI) by Thermography, Fourier Transform Infrared Attenuated Total Reflectance Spectroscopy (FTIR-ATR) and Gillmore needle indentation mechanical testing. The FTIR-ATR spectra showed the formation of metal carboxylates within the cements and enabled the stabilization time (ST) to be determined and the thermographic camera measured the temperature field images in the sample.

Discrimination of soils managed with different sources of fertilization and plant species in organic and conventional farming through near-infrared spectroscopy and chemometrics.

Background: The combination of near-infrared (NIR) spectroscopy and chemometrics can be used to group or discriminate soils based on spectral response. In this study, we conducted discrimination and classification analyses on soils managed with different sources of fertilization and plant species grown in organic and conventional farming systems.

Results: Principal component analysis explained 96% (PC1) and 3% (PC2) of the data variability and separated the soil samples of organic and conventional management systems.

Nanoencapsulated hypericin in P-123 associated with photodynamic therapy for the treatment of dermatophytosis.

The antifungal application of photodynamic therapy (PDT) has been widely explored. According to superficial nature of tinea capitis and the facility of application of light sources, the use of nanoencapsulated hypericin in P-123 associated with PDT (P123-Hy-PDT) has been a poweful tool to treat this pathology. Thus, the aim of this study was to evaluate the efficiency of P123-Hy-PDT against planktonic cells and in a murine model of dermatophytosis caused by Microsporum canis.

Optimizing reaction conditions and experimental studies of selective catalytic reduction of NO by CO over supported SBA-15 catalyst.

Selective catalytic reduction of NO with CO (CO-SCR) was investigated based on optimizing the operating conditions by response surface methodology (RSM) and by appropriately choosing the supported SBA-15 catalysts. The effects of the CO-SCR reaction parameters such as NO:CO molar ratios and oxygen concentrations on the catalytic performance were determined by RSM to evaluate the NO conversion using a first-order polynomial model. The CuO/SBA-15 and FeO/SBA-15 catalysts were synthesized by a hydrothermal method and characterized by X-ray diffraction (XRD), atomic absorption spectroscopy (AAS), N adsorption-desorption (BET), scanning electron microscopy coupled to energy dispersive X-Ray spectroscopy (SEM-EDS), and Fourier transform infrared spectroscopy (FTIR) to investigate the physicochemical properties of the solids.

Determining Potential Hosts of Melanaphis sacchari (Hemiptera: Aphididae) in the Louisiana Agroecoscape.

Although Melanaphis sacchari Zehntner (Hemiptera: Aphididae) is known worldwide for its injury to sugarcane, Saccharum officinarum L., and sorghum, Sorghum bicolor (L.) Moench, M.

Assessment of the implementation of the Leprosy Control Program in Camaragibe, Pernambuco State, Brazil.

Objective: to assess the implementation of the actions of the Leprosy Control Program in Camaragibe, Pernambuco State, Brazil.

Methods: evaluative research with 'implementation analysis', based on criteria, indicators and parameters guided from the construction of the Logic Model; four components were assessed - management, health care, epidemiological surveillance, health education and communication -; direct observation/questionnaire was used, as well as data from the Information System for Notifiable Diseases.

Results: the implementation of the program was incipient (58.

Subjective memory complaints and their relation with verbal fluency in active older people.

Purpose: To verify subjective memory complaints and their relation to verbal fluency in older people participating in community groups.

Methods: An epidemiological quantitative study performed in community groups for older people in Florianópolis, state of Santa Catarina, Brazil. Data were collected by structured interview using the Memory Complaint Questionnaire (MAC-Q) and the Verbal Fluency Test (VFT) by semantic categories "animals/minute".

Fractionation of rare earth and other trace elements in crabs, Ucides cordatus, from a subtropical mangrove affected by fertilizer industry.

Fractionation of rare earth elements (REE) and other trace metal concentrations (Th, U, Cd, Cr, Cu, Ni, Pb, and Zn) between mangrove sediments and claw muscles and shells of male crabs (Ucides cordatus) from a subtropical estuary highly impacted by fertilizer industry activities was investigated. This is the first record of REE distribution in these organisms, and the results showed higher accumulations of these metals, U and Th in shells, probably related to the replacement of Ca during molting. Contents of Cd, Cr and Ni were similar in both tissues, but Cu, Zn and Pb were mostly accumulated in the claw muscle with concentrations above those considered safe for human consumption according to the Brazilian legislation.

Diet-Induced Maternal Obesity Alters Insulin Signalling in Male Mice Offspring Rechallenged with a High-Fat Diet in Adulthood.

Modern lifestyle has resulted in an increase in the prevalence of obesity and its comorbidities in pregnant women and the young population. It has been well established that the consumption of a high-fat diet (HFD) has many direct effects on glucose metabolism. However, it is important to assess whether maternal consumption of a HFD during critical periods of development can lead to metabolic changes in the offspring metabolism.

Local and serum levels of adipokines in patients with obesity after periodontal therapy: one-year follow-up.

Aim: This study evaluated the effects of scaling and root planing (SRP) on gingival crevicular fluid (GCF) and serum levels of adipokines in patients with chronic periodontitis (CP) with or without obesity.

Methods: Twenty patients with obesity and 20 patients without obesity, all with CP, received SRP. Serum and GCF levels of resistin, adiponectin, leptin, tumour necrosis factor [TNF]-α and interleukin [IL]-6 were evaluated by enzyme-linked immunosorbent assay at baseline, 3, 6 and 12 months post-therapy.

Keratosis pilaris and prevalence of acne vulgaris: a cross-sectional study.

Background: Acne vulgaris has an important genetic predisposition, as well as keratosis pilaris. Clinical observations suggest that patients with keratosis pilaris have less frequent or less severe acne breakouts; however, we found no studies on this regard

Objective: To determine if the presence of keratosis pilaris is associated with lower prevalence and severity of acne.

Methods: A cross-sectional study was conducted with dermatology outpatients aged between 14 and 35 years.

Towards in situ fluorescence spectroscopy and microscopy investigations of asphaltene precipitation kinetics.

We perform a spectroscopic analysis of asphaltene in solution and in crude oil with the goal of designing an optical probe of asphaltene precipitation inside high-pressure cells. Quantitative analysis of steady-state spectroscopic data is employed to identify fluorescence and Raman contributions to the observed signals. Time-resolved fluorescence spectroscopy indicates that fluorescence lifetime can be used as a spectroscopic probe of asphaltene in crude oil.