Assessment of local blood flow with laser Doppler flowmetry in irradiated mandibular and frontal bone, an experiment in Göttingen minipigs.

Purpose: The aim of this study was to investigate local blood flow changes in the mandibular bone compared to the os frontale after irradiation in various doses.

Materials And Methods: This study used an animal experiment with 16 female Göttingen minipigs. Three groups of four animals were irradiated with equivalent doses of 25, 50 or 70 Gray on the mandible and os frontale and four animals served as control.