Publications by authors named "Moning Guo"

There are few data on the comorbidity of diabetes in Chinese patients with depression. We aimed to calculate the prevalence and explore risk factors of type 2 diabetes mellitus (T2DM) among depression inpatients from 2005 to 2018 in Beijing. This study is a cross-sectional study.

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Existing researches had primarily investigated the associations between various air pollutants and the risk of coronary heart disease (CHD) or diabetes mellitus (DM) separately. However, the significance and effects of PM and its components in patients with CHD and comorbid DM (CHD-DM) remain unclear. Patient data was sourced from the Beijing Municipal Health Commission Information Centre between January 1, 2014, and December 31, 2018.

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Background: Ambient temperatures and PM can trigger myocardial infarction (MI), while little is known about the complex interplay between these two factors on MI, especially morbidity.

Objectives: To investigate bidirectional effect modifications of temperature and PM on MI morbidity and mortality.

Methods: A time-stratified case-crossover study was conducted utilizing high-resolution data of temperature and PM, along with 498,077 MI cases from the citywide registry in Beijing, China from 2007 to 2021.

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Background: In 2015, the Chinese Government launched the coal to clean heating policy (CHP), designed to improve air quality and health in China. The CHP banned household coal burning and provided subsidies for clean electric or gas-powered heating for millions of peri-urban and rural households. We aimed to investigate whether the CHP affected the incidence of acute myocardial infarction in Beijing townships.

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  • * Data was collected from over 81,000 patients between 2013 and 2017, revealing that 21.1% were readmitted due to cardiovascular issues, with an average PM concentration of 62.8μg/m.
  • * A 10μg/m increase in PM levels raised readmission risk by 0.48%, with those having stents at vessel bifurcation experiencing a much higher excess risk of 4.12%.
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  • This study analyzed data from hospitals and vaccine administration records in Beijing, focusing on individuals vaccinated between January 2016 and December 2018 who experienced acute cardiovascular events.
  • The research involved 1,647 participants, revealing that the risk of cardiovascular events was reduced to 0.76 times the baseline level during 29-365 days post-vaccination.
  • The protective effect of the influenza vaccine was stronger in younger people and those without a history of cardiovascular issues, indicating that vaccines might help prevent cardiovascular diseases.
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Background: Developing countries face an "obesity epidemic," particularly affecting children and younger adults. While obesity is a known risk factor for 12 types of cancer, primarily affecting older populations, its impact on younger generations is understudied.

Methods: This study analyzed data from a population-based cancer registry covering 14.

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  • - A new term, small and vulnerable newborns (SVN), is proposed to collectively assess preterm births, small for gestational age (SGA), and low birth weight (LBW) in identifying high-risk newborns.
  • - The incidence of high-risk newborns has increased from 9.82% to 10.96% between 2013 and 2022 among a study of over 2 million newborns, highlighting the importance of the SVN definition which incorporates various risk factors like maternal age, first-time motherhood, and multiple births.
  • - Public health practices should adopt this new framework to better identify and address high-risk cases, particularly focusing on preventing issues related to multiple births and the implications for first
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  • Socioeconomic development has led to more older pregnancies and women having multiple children, which poses risks to both mothers and infants.
  • The report highlights that as the number of previous pregnancies (parities) increases, there are more older mothers and less women with higher education, while these women are also more likely to experience preterm births and larger babies.
  • Understanding pregnancy characteristics based on the number of past pregnancies can help create targeted public health strategies to improve pregnancy outcomes.*
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Background: Sex is a crucial factor in the development, progression, and treatment of cancer, making it vital to examine cancer incidence trends by sex for effective prevention strategies.

Objective: This study aimed to assess the incidence of cancer in China between 2007 and 2021, with a focus on sex-based trends.

Methods: A population-based cancer registry comprising 14.

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Purpose: As one of the pioneering pilot cities in China's extensive Diagnosis Related Groups (DRG) -based prepayment reform, Beijing is leading a comprehensive overhaul of the prepayment system, encompassing hospitals of varying affiliations and tiers. This systematic transformation is rooted in extensive patient group data, with the commencement of actual payments on March 15, 2022. This study aims to evaluate the effectiveness of DRG payment reform by examining how it affects the cost, volume, and utilization of care for patients with neurological disorders.

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Background: Ambient temperatures trigger hospitalisation, mortality, and emergency department visits for myocardial infarction (MI). However, nonoptimum temperature-related risks of fatal and nonfatal MI have not yet been compared.

Methods: From 2007 to 2019, 416,894 MI events (233,071 fatal and 183,823 nonfatal) were identified in Beijing, China.

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Background: We explored the impact of medical service fee adjustments on the choice of medical treatment for hypertensive patients in Beijing. We hope to provide decision-making reference to promote the realization of hierarchical diagnosis and treatment in Beijing.

Methods: According to the framework of modeling simulation research and based on the data of residents and medical institutions in Beijing, we designed three models of residents model, disease model and hospital model respectively.

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Article Synopsis
  • - Researchers studied the link between air pollutants and hospital admissions for cardiovascular disease (CVD) and respiratory diseases (RD) in elderly diabetic patients in Beijing from 2014 to 2019, finding that air pollution significantly impacts their health.
  • - A case-crossover method was used to analyze how short-term exposure to specific air pollutants affected hospital admissions, measuring their associations with CVD and RD within a week of exposure.
  • - Results indicated that for every increase in certain pollutants, like PM and CO, there was a notable rise in hospital admissions for both CVD and RD, with gaseous pollutants having a stronger impact than particulate matter among elder diabetic patients.
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  • This study examines acute myocardial infarction (AMI) mortality trends from 2007 to 2018 in Beijing, analyzing 94,106 deaths across 307 townships.
  • It finds that while overall AMI mortality has decreased, geographic disparities have grown, with areas experiencing greater health care access seeing a more significant decline in mortality rates.
  • The research suggests that improving health care accessibility in high-mortality areas may effectively reduce AMI-related deaths and address geographic inequalities in health outcomes.
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Background: To examine the association between urban neighborhood disorder and the recurrence risk of patients with acute myocardial infarction (AMI) in central Beijing, China.

Methods: Recurrent AMI was identified by the Beijing Monitoring System for Cardiovascular Diseases through the end of 2019 for patients discharged with AMI between 2007 and 2017. Cox proportional hazards models were performed to estimate associations between neighborhood disorder and AMI recurrence.

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Aims: Reports have suggested that COVID-19 vaccination may cause Type 1 diabetes (T1D), particularly fulminant T1D (FT1D). This study aimed to investigate the incidence of T1D in a general population of China, where>90% of the people have received three injections of inactivated SARS-Cov-2 vaccines in 2021.

Methods: A population-based registry of T1D was performed using data from the Beijing Municipal Health Commission Information Center.

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  • The study explored the connection between carbon monoxide (CO) exposure and chronic obstructive pulmonary disease (COPD) among patients with type 2 diabetes (T2DM) and hypertension in China, identifying significant risks linked to CO.
  • Analysis of over 459,000 COPD cases from 2014 to 2019 revealed that increases in CO correlated with higher admission rates for COPD, especially among patients with T2DM or hypertension.
  • The research indicated that women were generally more vulnerable to the effects of CO on COPD than men, with heightened risks observed in colder seasons compared to warmer ones.
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  • - This study evaluated how driving time to hospitals that provide percutaneous coronary intervention (PCI) affects mortality rates in patients suffering from acute myocardial infarction (AMI), based on data from over 142,000 cases in Beijing from 2013 to 2019.
  • - It was found that while many patients have good access to PCI-capable hospitals, there is a significant disparity between urban (71.2% living within 15 minutes) and peri-urban areas (31.8% living within 15 minutes), highlighting inequalities in healthcare access.
  • - The research showed that longer driving times to hospitals significantly increase the risk of death from AMI, with patients taking longer than 45 minutes having 44% higher odds of fatal
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  • - The study focused on creating a predictive model for functional outcomes at discharge for patients with traumatic brain injury (TBI) using machine learning techniques.
  • - Analyzing data from over 5,000 TBI patients, researchers used various models to determine which best predicted outcomes, finding that the random forest model performed the best in both internal and external validations.
  • - Key predictors for better outcomes included the Barthel Index score at admission, age, treatment type, neurosurgery status, and existing comorbidities.
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Background: Extensive studies have linked PM and PM with respiratory diseases (RD). However, few is known about causal association between PM and morbidity of RD. We aimed to assess the causal effects of PM on cause-specific RD.

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Objectives: To assess overall and gender-specific associations between marital status and out-of-hospital coronary death (OHCD) compared with patients surviving to hospital admission.

Design: A cross-sectional study based on linkage of administrative health databases.

Setting: Beijing, China.

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Air pollution and ischemic stroke (IS) are both vital factors affecting the health of Beijing citizens. This study aims at exploring the associations between air pollution, meteorology, and the hospital admission of IS (IS HA). Information on 476,659 IS inpatients in secondary and higher hospitals in Beijing from 2013 to 2018 were collected.

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Air pollutants' effect on ischemic stroke (IS) has been widely reported. But the effect of high-level concentrations during people's outdoor periods among hypertension patients was unknown. Peak-hour concentrations were defined considering air pollutants' high concentrations as well as people's outdoor periods.

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