Publications by authors named "Monika Schechinger"

Article Synopsis
  • Developing easy-to-use diagnostic tests for healthcare is crucial for improving patient outcomes, especially in areas lacking resources.
  • This paper introduces a paper-based device that detects miR-29a, linked to heart attacks, using both simple color changes and more complex SERS analysis.
  • While the colorimetric method provides quick feedback, the SERS option offers precision for further confirmation, making this dual approach a promising tool for diagnosing various diseases at the point of care.
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Epigenetic biomarkers are powerful tools for early disease detection and are particularly useful for elusive conditions like preeclampsia. Predicting preeclampsia at an early stage is one of the most important goals of maternal-fetal medicine. To this end, recent studies have identified microRNAs-such as microRNA-17-as early biomarkers for preeclampsia.

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DNA-functionalized nanoparticles, when paired with surface-enhanced Raman spectroscopy (SERS), can rapidly detect microRNA. However, widespread use of this approach is hindered by drawbacks associated with large and expensive benchtop Raman microscopes. MicroRNA-17 (miRNA-17) has emerged as a potential epigenetic indicator of preeclampsia, a condition that occurs during pregnancy.

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