Single-laboratory validation of a refined AOAC HPLC method 2005.06 for oysters, cockles, and clams in U.K. shellfish.

In 2009, a refined HPLC method based on AOAC Official Method 2005.06 was developed and validated for the determination of paralytic shellfish poisoning (PSP) in mussels. A single-laboratory validation study of this method was undertaken here for the analysis of PSP toxins in oysters, cockles, clams, and razor clams.