Publications by authors named "Monika Orvydaite"
Article Synopsis
- The study investigates the effects of electrical stimulation of the caudal ventrolateral medulla (CVLM) on blood pressure and survival in Wistar rats, suggesting a potential target for treating primary arterial hypertension (PAH).
- Twenty rats were divided into experimental and control groups, with significant decreases in arterial pressure and heart rate observed in the experimental group during the OFF stimulation phase, indicating the CVLM's role in blood pressure regulation.
- Though there are risks associated with stimulating medullary neural centers, this research highlights CVLM as a promising target for future deep brain stimulation therapies for drug-resistant hypertension, necessitating potential advancements in electrode technology for clinical use.
The control circuits of blood pressure have a strong neural regulatory element important in the pathogenesis of essential drug-resistant hypertension. Targeting lower medullary neural control mechanisms of blood pressure by electrical stimulation could be beneficial, and therefore, a novel device is needed. This paper presents a remotely programmable deep brain stimulator with an invasive continuous blood pressure monitoring system in a non-tethered rat model.
View Article and Find Full Text PDFBackground: Iodinated contrast media (ICM) is a frequently used compound in radiology. Non-immediate hypersensitivity reactions (HSR) appear when a patient leaves the department and usually are undocumented. True hypersensitivity in this group is rarely proved.
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