Effect of Exercise Repetitions on Arylesterase Activity of PON1 in Plasma of Average-Trained Men-The Dissociation between Activity and Concentration.

Exercise may increase the antioxidant capacity of plasma by stimulating antioxidant enzymes. The study aimed to measure the effect of three repetitions of acute exercise on arylesterase (ARE) activity of the paraoxonase 1 (PON1) enzyme. Eleven average-trained men (age 34.

Repetitions of Strenuous Exercise Consistently Increase Paraoxonase 1 Concentration and Activity in Plasma of Average-Trained Men.

Objectives: Oxidative stress, induced by physical activity, may stimulate the expression, release, and activity of certain antioxidant enzymes. We investigated the effect of three repeated bouts of strenuous exercise on paraoxonase 1 concentration (PON1c) and paraoxonase activity (PON).

Methods: Eleven average-trained healthy men (age 34.

Aerobic training modulates the effects of exercise-induced oxidative stress on PON1 activity: a preliminary study.

The aim of the study was to compare the effect of maximal exercise (ME) on paraoxonase (PON) and arylesterase (ARE) activity depending on lifestyle in respect to physical activity. The study was performed on 46 young men divided into two groups: sedentary (S) and physically active (PA). All participants performed ME on a treadmill.

The role of genetic (PON1 polymorphism) and environmental factors, especially physical activity, in antioxidant function of paraoxonase.

Paraoxonase 1 (PON1) is a member of a three-gene family (PON1, PON2, and PON3). PON1 activity dominates in human plasma. It is secreted from hepatic cells and is found in the circulation bound to high-density lipoproteins (HDLs).

Influence of different kind of clothing material on selected cardiovascular, respiratory and psychomotor parameters during moderate physical exercise.

Objectives: The aim of the experiment was to analyze the influence that the clothing material may have on human physiology and thermal comfort both at rest and physical effort to answer the question which fabric is better, a natural or a synthetic one.

Materials And Methods: We measured some psychomotor parameters: critical flicker frequency (CFF), reaction time to auditory/visual stimuli (RT), concentration of attention (CA); cardiovascular parameters: blood pressure (BP), heart rate (HR) and respiratory parameters: tidal volume (VT), minute ventilation (VE), oxygen consumption (VO2), carbon dioxide output (VCO2), respiratory exchange ratio (RER) in human volunteers before, during and after physical effort. The subjects performed a 15-min treadmill test on treadmill wearing clothes made of two different materials: 100% coarse wool and 100% acrylic.

Influence of thyrotropin-releasing hormone (TRH) dialyzed into the hippocampus on memory processes in rabbit.

There are conflicting reports on the influence of thyrotropin-releasing hormone (TRH) on the process of learning. We decided to study this problem using the paradigm of classical eyeblink conditioning as the animal model of learning processes. During the extinction training TRH in its natural form of pG1uTRH was applied into the rabbit hippocampus through a chronically implanted microdialysis probe.

Microdialysis of the brain structures: application in behavioral research on vasopressin and oxytocin.

In vivo microdialysis allows sampling of brain regions in conscious, freely moving animals. Moreover, the in vivo microdialysis allows to administer drugs directly into specific brain areas. Both are useful in behavioral studies.

Effect of excitatory amino acids on activity of vasopressinergic and oxytocinergic neurons.

A few compounds function as the excitatory amino acid (EAA) transmitters in the central nervous system (CNS), but glutamate (Glu) is the most important. Data on Glu participation in the control of vasopressinergic (AVP-ergic) and oxytocinergic (OXT-ergic) neuronal activity have been collected mainly on the basis of observations of hypothalamic AVP-ergic and OXT-ergic neurons. In vivo and in vitro experiments have demonstrated that Glu enhances bioelectric activity of the aforementioned neurons and increases AVP and OXT release.

Centrally applied oxytocin has no effect on eyelid conditioning in rabbits.

Objective: The classically conditioned rabbit eyelid reflex has proven to be useful for studying memory processes. The role of oxytocin (OXT) dialyzed into the hippocampus or caudate nucleus in the acquisition and extinction of this reflex was investigated.

Methods: Microdialysis probes were unilaterally, chronically, alternatively implanted into the mentioned brain structures.