Efficacy, quality of life, and safety of methotrexate versus interferon in head-to-head treatment in advanced stages of mycosis fungoides and Sezary syndrome. Prospective trial (NCT02323659).

Introduction: ESMO guidelines recommend interferon (IFN) and methotrexate (MTX) as first-line systemic therapies in mycosis fungoides (MF) and Sezary syndrome (SS).

Aim: A prospective, head-to-head trial comparing the efficacy and safety of INF-α and MTX as first-line treatment in MF/SS patients.

Material And Methods: Forty-three patients were enrolled in the trial.

Comparing radioactive tracers 18F-FDG and 18F-FLT in the staging of diffuse large B-cell lymphoma by PET/CT examination: A single-center prospective study.

Background: Positron emission tomography in combination with computer tomography (PET/CT) is a very important method of imaging patients with non-Hodgkin lymphomas (NHLs). It is used to define the initial grade of the disease and to assess early response to treatment and after chemotherapy. The most commonly used radioactive tracer is 18F-FDG, but 18F-FLT seems to be more specific.

F-fluoro-ethyl-tyrosine (F-FET) PET/CT as a potential new diagnostic tool in multiple myeloma: a preliminary study.

Aim Of The Study: The aim of this study was to analyse the diagnostic accuracy of F-fluoro-ethyl-tyrosine (F-FET) PET/CT tracer in multiple myeloma.

Material And Methods: The analysed group included: patients with newly diagnosed active myeloma (eight patients); in very good partial remission or complete remission (VGPR or CR) after treatment (nine patients); and with active disease after relapse (15 patients).

Results: In patients with newly diagnosed myeloma, 64 lesions were found using CT and 83 lesions using F-FET.

Follow-up of patients with mycosis fungoides after interferon α2b treatment failure.

Introduction: Treatment of T cell cutaneous lymphoma( CTCL) is a controversial subject and the effectiveness of treatment is still low.

Aim: Report of single center experience of management CTCL after progression after first line treatment.

Material And Methods: We present 41 patients with CTCL, 29 received interferon α2b in first line, and 12 of them received second line therapy.

Ocular blunt trauma during wood chopping as the reason for serious visual impairments.

Aim: The aim of the study was to present results of blunt ocular trauma with lens luxation to the vitreous during wood chopping.

Methods: A retrospective study of 15 patients treated in the Department of Ophthalmology between 2000-2011 who suffered from serious eye injury during wood chopping. As a standard surgical procedure, pars plana vitrectomy with lens removal and intraocular lens (IOL) implantation was applied in all cases.

Stability of cefuroxime in 1% and 5% buffered eye drops determined with HPLC method.

The aim of the studies was to develop formulary technologies of 1% and 5% eye drops containing cefuroxime with stability of at least 10-12 days. The stability was defined as the time required to reach the cutoff value of 10% degradation of cefuroxime in the drops, as determined using an HPLC assay. The drops should have such properties as optical clarity, pH in the range of 3.

[The microbiological analysis of the air in sewage treatment plant in the summer season].

The aim of this paper was the analysis of microbiological quality of air based on studies made in 2002-2004 in sewage treatment plant in Szczecin. The collection of samples was made with sampling by aspiration method with MAS-100, twice in 2002 and once time in 2003 and 2004. The studies were performed according to Polish Standards PN-89/Z-04111/01-02 and PN-81/C-04615/27 in one season (summer).